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Geoffrey V. Grandjean
Observed name:
Geoffrey Grandjean
Institution:
Sanford Burnham Prebys Medical Discovery Institute
Observed institutions:
The University of Texas MD Anderson Cancer Center,
Sanford Burnham Prebys Medical Discovery Institute,
University of Oxford,
Phusis Therapeutics (United States)
OpenAlex ID:
A5111889440
SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer
2010
·
Ahmed Ashour Ahmed
, Zhen Lu
, et al.
·
Cancer Cell
·
146
PDF
Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target
2016
·
Geoffrey Grandjean
, Petrus R. de Jong
, et al.
·
Cancer Research
·
78
Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel
2011
·
Ahmed Ashour Ahmed
, Xiaoyan Wang
, et al.
·
Cancer Research
·
54
PDF
A new HIF‐1α/RANTES‐driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice
2016
·
Mei Yee Koh
, Mihai Gagea
, et al.
·
Hepatology
·
46
PDF
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors
2019
·
Martin Indarte
, Roisin Puentes
, et al.
·
Cancer Research
·
37
Essential Attributes Identified in the Design of a Laboratory Information Management System for a High Throughput siRNA Screening Laboratory
2011
·
Geoffrey Grandjean
, Ryan Graham
, et al.
·
Combinatorial Chemistry & High Throughput Screening
·
3
Correction: An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors
2019
·
Martin Indarte
, Roisin Puentes
, et al.
·
Cancer Research
·
1
Abstract 4448: Identification of a small molecule inhibitor of aldolase A for the targeting of hypoxic cancer cells
2015
·
Petrus R. de Jong
, Geoffrey V. Grandjean
, et al.
·
Cancer Research
Abstract 2583: Refinement of inhibitors of the KRAS-signaling naocluster protein, CNKSR1, that block oncogenic KRAS signaling and growth
2015
·
D. Lynn Kirkpatrick
, Martin Indarte
, et al.
·
Cancer Research
Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth
2015
·
Geoffrey Grandjean
·
Digital Commons-TMC (Texas Medical Center)
PDF
Abstract 3836: A 3D high throughput RNA1 screen identifies the TLR4 kinase which alters spheroid architecture: a promising therapeutic strategy for pancreatic cancer.
2013
·
Geoffrey A. Bartholomeusz
, Alex Campos
, et al.
·
Cancer Research
Abstract 2076: Inhibiting glycolysis and HIF1α: a novel approach to cancer therapy.
2013
·
Geoffrey V. Grandjean
, John Kingston
, et al.
·
Cancer Research
Abstract 5505: A genome-wide siRNA screen for novel regulators of HIF-1α activity in normoxia and hypoxia
2010
·
John Kingston
, Geoffrey Grandjean
, et al.
·
Cancer Research
Abstract 2188: A high throughput RNAi screen for regulators of thioredoxin in pancreatic cancer cells identifies components of TGFβ-signaling as inducers of thioredoxin expression
2010
·
Geoffrey Grandjean
, Geoffrey Bartholomeusz
, et al.
·
Cancer Research
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Works count:
14
Citation count:
364
H-index:
5
I10-index:
5
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