Author

Lien B. Nguyen

Observed institutions: Rutgers, The State University of New Jersey, United States Department of Veterans Affairs, University of Arizona, University of British Columbia, University of South Florida, Veterans Health Administration, St. Paul's Hospital, University of Florida, VA New Jersey Health Care System, East Orange VA Medical Center, Rutgers New Jersey Medical School, Columbia University, Rockefeller University

OpenAlex ID: A5111939255

Biliary cholesterol excretion: A novel mechanism that regulates dietary cholesterol absorption

1998 · Ephraim Sehayek, Jennie G. Ono, et al. · Proceedings of the National Academy of Sciences · 170

Pathophysiology of apolipoprotein E deficiency in mice: relevance to apo E‐related disorders in humans

2001 · Mohammed H. Moghadasian, Bruce M. McManus, et al. · The FASEB Journal · 149

Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse?

2000 · Sarah Shefer, G. Stephen Tint, et al. · Journal of Neuroscience Research · 83

Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance

2001 · Sonya VanPatten, Narasimha Ranginani, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 81

Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: Studies in C57BL/6 apolipoprotein E knockout mice

2000 · Ephraim Sehayek, Sarah Shefer, et al. · Proceedings of the National Academy of Sciences · 69

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Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits

2000 · Guorong Xu, Benjamin L. Shneider, et al. · Journal of Lipid Research · 55

The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis

1988 · Lien B. Nguyen, Sarah Shefer, et al. · Metabolism · 54

The Effect of Increased Hepatic Sitosterol on the Regulation of 3–Hydroxy–3–Methylglutaryl—Coenzyme A Reductase and Cholesterol 7α–Hydroxylase in the Rat and Sitosterolemic Homozygotes

1994 · Sarah Shefer, Gerald Salen, et al. · Hepatology · 51

Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis

2001 · Thomas P. Johnston, Lien B. Nguyen, et al. · International Journal of Pharmaceutics · 48

Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: Diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function

1990 · Lien B. Nguyen, Gerald Salen, et al. · Metabolism · 47

Increasing dietary cholesterol induces different regulation of classic and alternative bile acid synthesis

1999 · Guorong Xu, Gerald Salen, et al. · Journal of Clinical Investigation · 44

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Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

1998 · Akira Honda, Gerald Salen, et al. · Journal of Lipid Research · 44

7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemli-Opitz syndrome skin fibroblasts

1998 · Megumi Honda, G.S. Tint, et al. · Journal of Lipid Research · 42

Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: Effects of apolipoprotein E deficiency and probucol or phytosterol treatment

2001 · Mohammed H. Moghadasian, Lien B. Nguyen, et al. · Metabolism · 36

Comparative regulation of hepatic sterol 27-hydroxylase and cholesterol 7α-hydroxylase activities in the rat, guinea pig, and rabbit: Effects of cholesterol and bile acids

1999 · Lien B. Nguyen, Guorong Xu, et al. · Metabolism · 35

Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion

1998 · Guorong Xu, Gerald Salen, et al. · Journal of Lipid Research · 29

Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: Sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis

1994 · Lien B. Nguyen, Gerald Salen, et al. · Metabolism · 28

Glycocholic acid and glycodeoxycholic acid but not glycoursocholic acid inhibit bile acid synthesis in the rabbit

1992 · Guorong Xu, Gerald Salen, et al. · Gastroenterology · 26

Removal of the bile acid pool upregulates cholesterol 7α-hydroxylase by deactivating FXR in rabbits

2002 · Guorong Xu, Lu-xing Pan, et al. · Journal of Lipid Research · 21

Rapid identification of smith-lemlip-opitz syndrome homozygotes and heterozygotes (carriers) by measurement of deficient 7-dehydrocholesterol-Δ7-reductase activity in fibroblasts

1997 · Sarah Shefer, Gerald Salen, et al. · Metabolism · 20

Sitosterolemia: opposing effects of cholestyramine and lovastatin on plasma sterol levels in a homozygous girl and her heterozygous father

1996 · Margaret M. Cobb, Gerald Salen, et al. · Metabolism · 20

Regulation of early cholesterol biosynthesis in rat liver: Effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities

1998 · Akira Honda, Gerald Salen, et al. · Hepatology · 19

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Effects of Food Composition on the Bioavailability of Vitamin B-6 in the Rat

1983 · Lien B. Nguyen, Jesse F. Gregory · Journal of Nutrition · 18

Modification of Hemoglobin by Acetaldehyde: A Time Course Study by High Pressure Liquid Chromatography

1984 · Lien B. Nguyen, Charles M. Peterson · Alcoholism Clinical and Experimental Research · 17

Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin

2001 · Lien B. Nguyen, Sarah Shefer, et al. · Journal of Lipid Research · 16

Works count: 35

Citation count: 1,271

H-index: 20

I10-index: 27