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Stuart L. Emanuel

Identification and sequence of an accessory factor required for activation of the human interferon γ receptor
1994 · Jaemog Soh, Robert J. Donnelly, et al. · Cell · 262
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors: Synthesis and Evaluation of Biological Activities
2005 · Ronghui Lin, Peter J. Connolly, et al. · Journal of Medicinal Chemistry · 126
The In vitro and In vivo Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases
2005 · Stuart Emanuel, Catherine A. Rugg, et al. · Cancer Research · 125
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Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors
2007 · Ronghui Lin, George Chiu, et al. · Bioorganic & Medicinal Chemistry Letters · 122
Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor
2006 · Shenlin Huang, Ronghui Lin, et al. · Bioorganic & Medicinal Chemistry Letters · 110
EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain.
1991 · D.R. Hurwitz, S.L. Emanuel, et al. · Journal of Biological Chemistry · 101
Discovery of anticancer agents of diverse natural origin
2009 · A. Douglas Kinghorn, Esperanza J. Carcache de Blanco, et al. · Pure and Applied Chemistry · 100
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Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors
2005 · Gee-Hong Kuo, Alan DeAngelis, et al. · Journal of Medicinal Chemistry · 92
Structures of Adnectin/Protein Complexes Reveal an Expanded Binding Footprint
2012 · Vidhyashankar Ramamurthy, Stanley R. Krystek, et al. · Structure · 87
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4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors
2008 · Guozhang Xu, Marta C. Abad, et al. · Bioorganic & Medicinal Chemistry Letters · 87
The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity
2015 · Benjamin A. Seigal, William H. Connors, et al. · Journal of Medicinal Chemistry · 85
Synthesis and Discovery of Macrocyclic Polyoxygenated Bis-7-azaindolylmaleimides as a Novel Series of Potent and Highly Selective Glycogen Synthase Kinase-3β Inhibitors
2003 · Gee-Hong Kuo, Catherine Prouty, et al. · Journal of Medicinal Chemistry · 81
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents
2007 · Ronghui Lin, Peter J. Connolly, et al. · Bioorganic & Medicinal Chemistry Letters · 80
Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2
2011 · A V Purandare, T M McDevitt, et al. · Leukemia · 77
A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor
2011 · Stuart L. Emanuel, Linda J. Engle, et al. · mAbs · 72
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Novel Indolylindazolylmaleimides as Inhibitors of Protein Kinase C-β: Synthesis, Biological Activity, and Cardiovascular Safety
2004 · Han-Cheng Zhang, Claudia K. Derian, et al. · Journal of Medicinal Chemistry · 61
Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor
2006 · Jennifer A. Seamon, Catherine A. Rugg, et al. · Molecular Cancer Therapeutics · 57
Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3
2003 · Han-Cheng Zhang, Kimberly B. White, et al. · Bioorganic & Medicinal Chemistry Letters · 56
Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases
2008 · Guozhang Xu, Lily Lee Searle, et al. · Bioorganic & Medicinal Chemistry Letters · 55
Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621
2006 · Shenlin Huang, Peter J. Connolly, et al. · Bioorganic & Medicinal Chemistry Letters · 46
4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation
2007 · Terry V. Hughes, Stuart L. Emanuel, et al. · Bioorganic & Medicinal Chemistry Letters · 45
A Vascular Endothelial Growth Factor Receptor-2 Kinase Inhibitor Potentiates the Activity of the Conventional Chemotherapeutic Agents Paclitaxel and Doxorubicin in Tumor Xenograft Models
2004 · Stuart Emanuel, Robert H. Gruninger, et al. · Molecular Pharmacology · 41
Sublocalization of the human interferon-gamma receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation.
1994 · J.R. Cook, S.L. Emanuel, et al. · Journal of Biological Chemistry · 38
Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors
2007 · Stuart L. Emanuel, Terry V. Hughes, et al. · Molecular Pharmacology · 37
(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells
2005 · Chih Y. Ho, Donald W. Ludovici, et al. · Journal of Medicinal Chemistry · 35
Works count: 62
Citation count: 2,465
H-index: 28
I10-index: 42
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