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S. E. Clarke

Observed names: S E Clarke, S. Clarke, S. E. CLARKE, SE Clarke
OpenAlex ID: A5111977379
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
1995 · S. J. Baldwin, J. C. Bloomer, et al. · Xenobiotica · 296
A Critical Evaluation of the Experimental Design of Studies of Mechanism Based Enzyme Inhibition, with Implications for In Vitro-In Vivo Extrapolation
2006 · F. Ghanbari, K. Rowland-Yeo, et al. · Current Drug Metabolism · 133
In vitro assessment of human cytochrome P450
1998 · S. E. CLARKE · Xenobiotica · 119
Utility of metabolic stability screening: comparison ofin vitroandin vivoclearance
2001 · S. E. Clarke, P. Jeffrey · Xenobiotica · 114
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver.
1995 · S E Clarke, A W Harrell, et al. · Drug Metabolism and Disposition · 104
Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron.
1994 · JC Bloomer, SJ Baldwin, et al. · British Journal of Clinical Pharmacology · 89
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Characterization of the inhibition of P4501A2 by furafylline
1994 · S. E. Clarke, A. D. Ayrton, et al. · Xenobiotica · 74
In vitro identification of the P450 enzymes responsible for the metabolism of ropinirole.
1997 · J C Bloomer, S E Clarke, et al. · PubMed · 39
Metabolism and disposition of14C-granisetron in rat, dog and man after intravenous and oral dosing
1994 · S. E. Clarke, N. E. Austin, et al. · Xenobiotica · 29
Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine
1995 · J. C. Bloomer, S. E. Clarke, et al. · Xenobiotica · 27
Rapid Screening of Taxol Metabolites in Human Microsomes by Liquid Chromatography/ Electrospray Ionization-Mass Spectrometry
1996 · G. K. Poon, J. Wade, et al. · Rapid Communications in Mass Spectrometry · 26
Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent.
1994 · A W Harrell, S M Wheeler, et al. · Drug Metabolism and Disposition · 15
Characterisation of diethoxyfluorescein as a substrate for the human cytochrome P450 enzymes 2C8 and 3A4.
2001 · J. C. Bloomer, R Bambal, et al. · Drug Metabolism Reviews
The simultaneous metabolism and binding of testosterone and diazepam in a recombinant CYP3A4 enzyme system. At 12th International Symposium on Microsomes and Drug Oxidations, Montpellier, France.
1998 · Kk.E Kenworthy, S. E. Clarke, et al. · Research Explorer (The University of Manchester)
Works count: 14
Citation count: 1,065
H-index: 12
I10-index: 12
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