Author

Edward Kyu-Ho Han

Observed names: E K Han, E Kyu-Ho Han, E. K.-H. Han, E. Kyu-Ho Han, EK Han, Edward Han, Edward K. Han, Edward K.-H. Han, Edward Kyu-ho Han

Observed institutions: Queens College, CUNY, Albert Einstein College of Medicine, Sanford Burnham Prebys Medical Discovery Institute, Columbia University Irving Medical Center, AbbVie (United States), Abbott (United Kingdom), Abbott (United States), Herbert Irving Comprehensive Cancer Center, Columbia University

OpenAlex ID: A5112212225

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

2007 · Cherrie K. Donawho, Yan Luo, et al. · Clinical Cancer Research · 784

Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

2005 · Yan Luo, Alexander R. Shoemaker, et al. · Molecular Cancer Therapeutics · 234

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines

1999 · Jin T.E Lim, Gary A Piazza, et al. · Biochemical Pharmacology · 208

ABBV-399, a c-Met Antibody–Drug Conjugate that Targets Both MET –Amplified and c-Met–Overexpressing Tumors, Irrespective of MET Pathway Dependence

2016 · Jieyi Wang, Mark G. Anderson, et al. · Clinical Cancer Research · 154

PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.

1996 · A M Cacace, M Ueffing, et al. · PubMed · 154

Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis.

1996 · E K Han, M Begemann, et al. · PubMed · 138

Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.

1997 · I B Weinstein, M Begemann, et al. · PubMed · 124

Modulation of paclitaxel resistance by annexin IV in human cancer cell lines

2000 · E Kyu-Ho Han, S K Tahir, et al. · British Journal of Cancer · 97

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Acquired Resistance to Combination Treatment with Temozolomide and ABT-888 Is Mediated by Both Base Excision Repair and Homologous Recombination DNA Repair Pathways

2009 · Xuesong Liu, Edward K. Han, et al. · Molecular Cancer Research · 93

Characterization of the glucose-induced inactivation of maltose permease in Saccharomyces cerevisiae

1996 · I Medintz, H Jiang, et al. · Journal of Bacteriology · 90

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

2006 · Keith W. Woods, John P. Fischer, et al. · Bioorganic & Medicinal Chemistry · 87

Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth.

1995 · E K Han, A Sgambato, et al. · PubMed · 87

Discovery of 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases

2009 · Zhi-Fu Tao, Lisa A. Hasvold, et al. · Journal of Medicinal Chemistry · 86

Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis

1999 · E. K.-H. Han, S.-C. Ng, et al. · APOPTOSIS · 73

Effects of sulindac and its metabolites on growth and apoptosis in human mammary epithelial and breast carcinoma cell lines

1998 · Edward Kyu-Ho Han, Nadir Arber, et al. · Breast Cancer Research and Treatment · 71

A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes

1997 · N Arber, EK Han, et al. · Gastroenterology · 69

A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.

2001 · S K Tahir, E K Han, et al. · PubMed · 66

Identification of the major phosphorylation domain of murine mdr1b P-glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites.

1993 · G A Orr, E K Han, et al. · Journal of Biological Chemistry · 61

Overexpression of cyclin E in the HC11 mouse mammary epithelial cell line is associated with growth inhibition and increased expression of p27(Kip1).

1996 · A Sgambato, E K Han, et al. · PubMed · 59

Optimal Classes of Chemotherapeutic Agents Sensitized by Specific Small-Molecule Inhibitors of Akt In Vitro and In Vivo

2005 · Yan Shi, Xuesong Liu, et al. · Neoplasia · 54

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Blocking CHK1 Expression Induces Apoptosis and Abrogates the G2 Checkpoint Mechanism

2001 · Yan Luo, Shayna K. Rockow-Magnone, et al. · Neoplasia · 54

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Modulation of drug resistance by α-tubulin in paclitaxel-resistant human lung cancer cell lines

2000 · E. Kyu-Ho Han, L. Gehrke, et al. · European Journal of Cancer · 54

Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells

2001 · Xuesong Liu, Yan Shi, et al. · Neoplasia · 47

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Characterization of Akt overexpression in MiaPaCa-2 cells: prohibitin is an Akt substrate both in vitro and in cells.

2008 · Edward Kyu-Ho Han, Thomas Mcgonigal, et al. · PubMed · 46

Functional analysis of focal adhesion kinase (FAK) reduction by small inhibitory RNAs.

2004 · Edward Kyu-Ho Han, Thomas Mcgonigal, et al. · PubMed · 39

Works count: 44

Citation count: 3,254

H-index: 28

I10-index: 33