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Christopher Halliday
Observed names:
CHRISTOPHER HALLIDAY,
Halliday, Christopher
Observed institutions:
University of Calgary,
Resverlogix (Canada)
OpenAlex ID:
A5112335251
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection
2021
·
Richard J. Mills
, Sean J. Humphrey
, et al.
·
Cell
·
227
PDF
Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism
2019
·
Laura M. Tsujikawa
, Li Fu
, et al.
·
Clinical Epigenetics
·
128
PDF
RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease
2016
·
Dean Gilham
, Sylwia Wasiak
, et al.
·
Atherosclerosis
·
117
Apabetalone downregulates factors and pathways associated with vascular calcification
2018
·
Dean Gilham
, Laura M. Tsujikawa
, et al.
·
Atherosclerosis
·
65
PDF
Downregulation of the Complement Cascade In Vitro, in Mice and in Patients with Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX-208)
2017
·
Sylwia Wasiak
, Dean Gilham
, et al.
·
Journal of Cardiovascular Translational Research
·
51
PDF
Apabetalone Mediated Epigenetic Modulation is Associated with Favorable Kidney Function and Alkaline Phosphatase Profile in Patients with Chronic Kidney Disease
2018
·
Ewelina Kulikowski
, Christopher Halliday
, et al.
·
Kidney & Blood Pressure Research
·
46
Benefit of Apabetalone on Plasma Proteins in Renal Disease
2017
·
Sylwia Wasiak
, Laura M. Tsujikawa
, et al.
·
Kidney International Reports
·
42
PDF
Apabetalone lowers serum alkaline phosphatase and improves cardiovascular risk in patients with cardiovascular disease
2019
·
Mathias Haarhaus
, Kausik K. Ray
, et al.
·
Atherosclerosis
·
38
PDF
Relation of insulin treatment for type 2 diabetes to the risk of major adverse cardiovascular events after acute coronary syndrome: an analysis of the BETonMACE randomized clinical trial
2021
·
Gregory G. Schwartz
, Stephen J. Nicholls
, et al.
·
Cardiovascular Diabetology
·
28
PDF
Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes
2016
·
Sylwia Wasiak
, Dean Gilham
, et al.
·
Data in Brief
·
17
PDF
Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro , in Mice and in Patients with Cardiovascular Disease
2020
·
Sylwia Wasiak
, Dean Gilham
, et al.
·
Cardiovascular Therapeutics
·
15
PDF
Corrigendum to “RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease” [Atherosclerosis 247 (2016) 48–57]
2016
·
Dean Gilham
, Sylwia Wasiak
, et al.
·
Atherosclerosis
·
5
Sp071apabetalone (rvx-208), a Selective Bromodomain and Extra-terminal (bet) Protein Inhibitor, Decreases Abundance and Activity of Complement Proteins in Vitro, in Mice and in Clinical Studies
2016
·
Norman Cw Wong
, Kamyar Kalantar-Zadeh
, et al.
·
Nephrology Dialysis Transplantation
·
3
PDF
Apabetalone, an Epigenetic Bet Inhibitor in a Phase 3 Trial, Inhibits Vascular Inflammation and Cellular Adhesion Leading to Beneficial Outcomes in Cvd Patients
2019
·
Laura Tsujikawa
, Li Fu
, et al.
·
Journal of the American College of Cardiology
·
2
PDF
Sp425effects of Apabetalone (rvx-208) on Serum Albumin in Subjects With Cvd, Diabetes and Chronic Kidney Disease; a Post-hoc Analysis of the Assure and Sustain Clinical Trials
2017
·
Ewelina Kulikowski
, Christopher Halliday
, et al.
·
Nephrology Dialysis Transplantation
·
2
PDF
Apabetalone (rvx-208) Lowers Cardiovascular Disease (cvd) in Diabetes Mellitus by a Mechanism Involving Microbiome Mediated Activity on the Complement Pathway
2017
·
Norman C. Wong
, Ewelina Kulikowski
, et al.
·
Journal of the American College of Cardiology
·
2
PDF
Fp330apabetalone, a Selective Bromodomain and Extra-terminal (bet) Protein Inhibitor, Reduces Serum Fgf23 in Cardiovascular Disease and Chronic Kidney Disease Patients
2019
·
Kamyar Kalantar-Zadeh
, Carmine Zoccali
, et al.
·
Nephrology Dialysis Transplantation
·
1
Abstract 671: Hepatic Expression of C-Reactive Protein is Epigenetically Regulated by BET Proteins and Inhibited by Apabetalone (RVX-208) in vitro and in CVD Patients
2019
·
Sylwia Wasiak
, Dean Gilham
, et al.
·
Arteriosclerosis Thrombosis and Vascular Biology
·
1
Apabetalone (RVX-208) Lowers Risk of Major Adverse Cardiovascular Events (MACE) in T2D Patients with CVD By Attenuating Monocyte Adhesion to Endothelial Cells
2018
·
Laura Tsujikawa
, Ewelina Kulikowski
, et al.
·
Atherosclerosis Supplements
·
1
BET inhibitor apabetalone (RVX-208) downregulates the complement cascade in primary human hepatocytes, in mice and in cardiovascular disease human patients
2017
·
Sylwia Wasiak
, Dean Gilham
, et al.
·
Molecular Immunology
·
1
Abstract 163: Apabetalone (RVX-208) Has Anti-atherosclerotic, Anti-Thrombotic and Anti-Inflammatory Effects in Patients With Cardiovascular Disease (CVD)
2016
·
Ewelina Kulikowski
, Sylwia Wasiak
, et al.
·
Arteriosclerosis Thrombosis and Vascular Biology
·
1
Abstract 338: Effects of RVX-208 a Selective Bromodomain Extra-Terminal Protein Inhibitor Beyond Raising ApoA-I/HDL.
2015
·
Norman C Wong
, Ewelina Kulikowski
, et al.
·
Arteriosclerosis Thrombosis and Vascular Biology
·
1
Permissive Blood Pressure Targets in Pediatric Critical Care
2026
·
David P. Inwald
, Emma Laing
, et al.
·
JAMA
PDF
Mo072apabetalone Downregulates Fibrotic, Inflammatory and Calcific Processes in Renal Mesangial Cells Which May Contribute to Reduced Cardiac Events Observed in Ckd Patients
2021
·
Dean Gilham
, Li Fu
, et al.
·
Nephrology Dialysis Transplantation
Apabetalone, an Inhibitor of BET Proteins, Downregulates Alkaline Phosphatase and Improves Cardiovascular Risk
2020
·
Dean Gilham
, Laura Tsujikawa
, et al.
·
Journal of the American Society of Nephrology
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Works count:
55
Citation count:
794
H-index:
11
I10-index:
11
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