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Martin J. I. Andrews

Observed names: Andrews, Martin, M. Andrews, M. J. I. ANDREWS, Martin Andrews, Martin J I Andrews, Martin J.I Andrews, Martin J.I. Andrews, Martin James Inglis Andrews, Martin J. Andrews
Institution: Galapagos (Belgium)
ORCID: 0009-0007-7471-7652
Observed ORCID: 0009-0007-7471-7652
OpenAlex ID: A5112470636
Forming stable helical peptides using natural and artificial amino acids
1999 · Martin J.I. Andrews, Alethea B. Tabor · Tetrahedron · 171
A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ
2013 · Hilde M. van der Schaar, Pieter Leyssen, et al. · Antimicrobial Agents and Chemotherapy · 119
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Discovery ofN-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-lH-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent
2017 · Steven E. Van der Plas, Hans Kelgtermans, et al. · Journal of Medicinal Chemistry · 65
Insights into Cyclin Groove Recognition
2003 · George Kontopidis, Martin J.I. Andrews, et al. · Structure · 62
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Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes
2004 · Martin J. I. Andrews, Campbell McInnes, et al. · Organic & Biomolecular Chemistry · 60
Identification and Characterization of Novel CFTR Potentiators
2018 · Maarten Gees, Sara Musch, et al. · Frontiers in Pharmacology · 47
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REPLACE: A Strategy for Iterative Design of Cyclin‐Binding Groove Inhibitors
2006 · Martin J. I. Andrews, George Kontopidis, et al. · ChemBioChem · 43
Identification of a Series of Compounds with Potent Antiviral Activity for the Treatment of Enterovirus Infections
2013 · Angus M. MacLeod, Dale R. Mitchell, et al. · ACS Medicinal Chemistry Letters · 42
Discovery of Clinical Candidate GLPG3970: A Potent and Selective Dual SIK2/SIK3 Inhibitor for the Treatment of Autoimmune and Inflammatory Diseases
2024 · Christophe Peixoto, Agnes Joncour, et al. · Journal of Medicinal Chemistry · 28
Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis
2021 · Steven E. Van der Plas, Hans Kelgtermans, et al. · Journal of Medicinal Chemistry · 26
Optimization of Selectivity and Pharmacokinetic Properties of Salt-Inducible Kinase Inhibitors that Led to the Discovery of Pan-SIK Inhibitor GLPG3312
2023 · Taouès Temal-Laib, Christophe Peixoto, et al. · Journal of Medicinal Chemistry · 24
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Truncation and Optimisation of Peptide Inhibitors of Cyclin‐Dependent Kinase 2‐Cyclin A Through Structure‐Guided Design
2009 · George Kontopidis, Martin J. Andrews, et al. · ChemMedChem · 24
Peptides Constrained by an Aliphatic Linkage between Two CαSites: Design, Synthesis, and Unexpected Conformational Properties of ani,(i+4)-Linked Peptide
2001 · Linda M. Alexander McNamara, Martin J. I. Andrews, et al. · The Journal of Organic Chemistry · 22
Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis
2012 · Martin J.I. Andrews, J. Andrew Clase, et al. · Bioorganic & Medicinal Chemistry Letters · 15
PI4KIII inhibitor enviroxime impedes the replication of the hepatitis C virus by inhibiting PI3 kinases
2018 · Leen Delang, Christian Harak, et al. · Journal of Antimicrobial Chemotherapy · 14
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Synthesis of an Orthogonally-Protected Bifunctional Amino Acid for Conformationally Constrained Peptides
1997 · Martin J.I Andrews, Alethea B Tabor* · Tetrahedron Letters · 12
Fitness and Virulence of a Coxsackievirus Mutant That Can Circumnavigate the Need for Phosphatidylinositol 4-Kinase Class III Beta
2013 · Hendrik Jan Thibaut, Hilde M. van der Schaar, et al. · Journal of Virology · 8
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Expediting drug discovery: recent advances in fast medicinal chemistry--optimization of hits and leads.
2006 · Paul J Edwards, Brigitte Allart, et al. · PubMed · 8
Targeted Delivery of Oligonucleotide–Peptide Conjugates for Enhanced Kidney-Specific Therapy
2025 · Morgane Mannes, Dora Mugoli Chigoho, et al. · Journal of Medicinal Chemistry · 5
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HBsAg Suppression by a New Series of HBV RNA Destabilizers: Discovery and Effects on In Vitro Neurite Outgrowth
2026 · Jacques Huck, Caroline Joannesse, et al. · Journal of Medicinal Chemistry · 3
Synthesis of a novel silicon bearing linker for solid phase synthesis
2004 · Robert Ramage, Martin J.I. Andrews, et al. · Tetrahedron Letters · 3
Unexpected conformational properties of a peptide constrained by an aliphatic link between the i and i+4 positions
2001 · Linda M.Alexander McNamara, Martin J.I Andrews, et al. · Tetrahedron Letters · 3
Discovery and Characterization of GLPG3808, a PAPD5/7 Inhibitor for Suppression of Hepatitis B Viral Infections
2026 · Oscar Mammoliti, Adeline Palisse, et al. · Journal of Medicinal Chemistry · 2
Correction to “Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis”
2021 · Steven E. Van der Plas, Hans Kelgtermans, et al. · Journal of Medicinal Chemistry
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BetaPhosphatidylinositol 4-Kinase Class III Mutant That Can Circumnavigate the Need Fitness and Virulence of a Coxsackievirus
2014 · Johan Neyts, Frank J. M. van Kuppeveld, et al.
Works count: 34
Citation count: 806
H-index: 14
I10-index: 16
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