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Caly Chien

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
2010 · Min Gao, Richard E. Nettles, et al. · Nature · 960
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An Open-Label, Multicenter, Phase I/II Study of JNJ-40346527, a CSF-1R Inhibitor, in Patients with Relapsed or Refractory Hodgkin Lymphoma
2015 · Bastian von Tresckow, Franck Morschhauser, et al. · Clinical Cancer Research · 125
Food effects on abiraterone pharmacokinetics in healthy subjects and patients with metastatic castration‐resistant prostate cancer
2015 · Kim N. Chi, Jennifer Spratlin, et al. · The Journal of Clinical Pharmacology · 110
Effect of Maternal Fluoxetine Administration on Uterine Blood Flow, Fetal Blood Gas Status, and Growth
2002 · Janna Leigh Morrison, Caly Chien, et al. · Pediatric Research · 81
Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
2014 · Paul M. Scola, Alan Xiangdong Wang, et al. · Journal of Medicinal Chemistry · 76
Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy
2015 · Mark C. Genovese, Elizabeth Hsia, et al. · The Journal of Rheumatology · 70
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Pharmacokinetic Drug–Drug Interaction of Apalutamide, Part 1: Clinical Studies in Healthy Men and Patients with Castration-Resistant Prostate Cancer
2020 · Ignacio Duran, Joan Carles, et al. · Clinical Pharmacokinetics · 58
Compartmental Absorption Modeling and Site of Absorption Studies to Determine Feasibility of an Extended-Release Formulation of an HIV-1 Attachment Inhibitor Phosphate Ester Prodrug
2013 · Jonathan Brown, Caly Chien, et al. · Journal of Pharmaceutical Sciences · 57
HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer
2018 · Mohammad Alyamani, Hamid Emamekhoo, et al. · Journal of Clinical Investigation · 56
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Fetal behavioural state changes following maternal fluoxetine infusion in sheep
2001 · Janna Leigh Morrison, Caly Chien, et al. · Developmental Brain Research · 55
FRESCO-2: A Global Phase III Study Investigating the Efficacy and Safety of Fruquintinib in Metastatic Colorectal Cancer
2021 · Arvind Dasari, Alberto Sobrero, et al. · Future Oncology · 53
Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)
2013 · Alicia Regueiro-Ren, Qiufen M. Xue, et al. · Journal of Medicinal Chemistry · 50
Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment 6. Preclinical and Human Pharmacokinetic Profiling of BMS-663749, a Phosphonooxymethyl Prodrug of the HIV-1 Attachment Inhibitor 2-(4-Benzoyl-1-piperazinyl)-1-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoethanone (BMS-488043)
2012 · John F. Kadow, Yasutsugu Ueda, et al. · Journal of Medicinal Chemistry · 49
Chronic Maternal Fluoxetine Infusion in Pregnant Sheep: Effects on the Maternal and Fetal Hypothalamic-Pituitary-Adrenal Axes
2004 · Janna L Morrison, K Wayne Riggs, et al. · Pediatric Research · 41
Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes
2019 · Ronald de Vries, Frank Jacobs, et al. · Drug Metabolism and Disposition · 39
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Impact on abiraterone pharmacokinetics and safety: Open‐label drug–drug interaction studies with ketoconazole and rifampicin
2014 · Apexa Bernard, Nicole Vaccaro, et al. · Clinical Pharmacology in Drug Development · 34
Single‐dose pharmacokinetic studies of abiraterone acetate in men with hepatic or renal impairment
2013 · Thomas Marbury, Eric Lawitz, et al. · The Journal of Clinical Pharmacology · 32
An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer
2018 · Bodine P. S. I. Belderbos, Ronald de Wit, et al. · Cancer Chemotherapy and Pharmacology · 27
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Efficacy and Safety Exposure–Response Relationships of Apalutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer
2020 · Carlos Perez-Ruixo, Oliver Ackaert, et al. · Clinical Cancer Research · 25
Pharmacokinetic Drug–Drug Interaction of Apalutamide, Part 2: Investigating Interaction Potential Using a Physiologically Based Pharmacokinetic Model
2020 · An Van den Bergh, Jan Snoeys, et al. · Clinical Pharmacokinetics · 25
Population Pharmacokinetics of Apalutamide and its Active Metabolite N-Desmethyl-Apalutamide in Healthy and Castration-Resistant Prostate Cancer Subjects
2019 · Carlos Pérez-Ruixo, Jonás Samuel Pérez-Blanco, et al. · Clinical Pharmacokinetics · 25
Maternal Fluoxetine Infusion Does Not Alter Fetal Endocrine and Biophysical Circadian Rhythms in Pregnant Sheep
2005 · Janna L. Mornson, Dan W. Rurak, et al. · Journal of the Society for Gynecologic Investigation · 18
Pharmacokinetics of abiraterone in healthy Japanese men: dose-proportionality and effect of food timing
2014 · Kouichi Inoue, Akira Shishido, et al. · Cancer Chemotherapy and Pharmacology · 17
Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study
2020 · Edwin M. Posadas, Kim N. Chi, et al. · Clinical Cancer Research · 16
Effect of Food on Abiraterone Pharmacokinetics: A Review
2017 · Caly Chien, Michael Smith, et al. · International Journal of Pharmacokinetics · 16
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Works count: 60
Citation count: 2,210
H-index: 21
I10-index: 29
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