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Odalys Gonzalez Paz

Observed names: Gonzalez Paz, Odalys, O Gonzalez Paz, O. Gonzalez Paz, O. Gonzalez-paz, Odalys Gonzalez-Paz, Paz, Odalys Gonzalez
OpenAlex ID: A5112913341
Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection
2008 · Vincenzo Summa, Alessia Petrocchi, et al. · Journal of Medicinal Chemistry · 653
Anthracycline cardiotoxicity
2011 · Pierantonio Menna, Odalys Gonzalez Paz, et al. · Expert Opinion on Drug Safety · 187
4,5-Dihydroxypyrimidine Carboxamides and N-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species
2006 · Vincenzo Summa, Alessia Petrocchi, et al. · Journal of Medicinal Chemistry · 104
Construction of an rtTA2s-m2/ttskid-Based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and Non-Human primates
2003 · Stefania Lamartina, Luisa Silvi, et al. · Molecular Therapy · 82
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Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors
2007 · Paola Pace, M. Emilia Di Francesco, et al. · Journal of Medicinal Chemistry · 80
Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones
2007 · Cristina Gardelli, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 67
Liver-Specific Alpha 2 Interferon Gene Expression Results in Protection from Induced Hepatitis
2000 · Luigi Aurisicchio, Paola Delmastro, et al. · Journal of Virology · 61
A Novel Series of Potent and Selective Ketone Histone Deacetylase Inhibitors with Antitumor Activity in Vivo
2008 · Philip Jones, Sergio Altamura, et al. · Journal of Medicinal Chemistry · 59
The Novel Anthracenedione, Pixantrone, Lacks Redox Activity and Inhibits Doxorubicinol Formation in Human Myocardium: Insight to Explain the Cardiac Safety of Pixantrone in Doxorubicin-Treated Patients
2012 · Emanuela Salvatorelli, Pierantonio Menna, et al. · Journal of Pharmacology and Experimental Therapeutics · 54
Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors
2008 · Ester Muraglia, Olaf Kinzel, et al. · Journal of Medicinal Chemistry · 53
Multidrug Resistance-Reversing Agents Increase Vinblastine Distribution in Normal Tissues Expressing the P-Glycoprotein but Do Not Enhance Drug Penetration in Brain and Testis
1997 · Margarita Arboix, Odalys Gonzalez Paz, et al. · Journal of Pharmacology and Experimental Therapeutics · 50
Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties
2009 · Olaf Kinzel, Laura Llauger-Bufi, et al. · Journal of Medicinal Chemistry · 46
Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features
2022 · Beatrice Simonis, Domenico Vignone, et al. · Journal of Colloid and Interface Science · 43
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Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System
2020 · Annalise Di Marco, Domenico Vignone, et al. · Cells · 38
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Application of an in Vitro Blood–Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington’s Disease
2019 · Annalise Di Marco, Odalys Gonzalez Paz, et al. · Molecular Pharmaceutics · 38
Distribution and activity of doxorubicin combined with SDZ PSC 833 in mice with P388 and P388/DOX leukaemia
1996 · T Colombo, O Gonzalez Paz, et al. · British Journal of Cancer · 35
Pharmacokinetic Characterization of Amrubicin Cardiac Safety in an Ex Vivo Human Myocardial Strip Model. II. Amrubicin Shows Metabolic Advantages over Doxorubicin and Epirubicin
2012 · Emanuela Salvatorelli, Pierantonio Menna, et al. · Journal of Pharmacology and Experimental Therapeutics · 33
Cyclic phosphoramidates as prodrugs of 2′-C-methylcytidine
2009 · Malte Meppen, Barbara Pacini, et al. · European Journal of Medicinal Chemistry · 31
Quantitative Prediction of Human Clearance Guiding the Development of Raltegravir (MK-0518, Isentress) and Related HIV Integrase Inhibitors
2009 · Ralph Laufer, Odalys Gonzalez Paz, et al. · Drug Metabolism and Disposition · 31
Modelling the Human Blood–Brain Barrier in Huntington Disease
2022 · Domenico Vignone, Odalys Gonzalez Paz, et al. · International Journal of Molecular Sciences · 25
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SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease
2004 · Savina Malancona, Stefania Colarusso, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase
2005 · C. Giuliano, F. Fiore, et al. · Xenobiotica · 22
A Structure-Guided Approach to an Orthogonal Estrogen-Receptor-Based Gene Switch Activated by Ligands Suitable for in Vivo Studies
2006 · Olaf Kinzel, Daniela Fattori, et al. · Journal of Medicinal Chemistry · 19
Paclitaxel induces significant changes in epidoxorubicin distribution in mice
1996 · T. Colombo, O. Gonzalez Paz, et al. · Annals of Oncology · 18
Sequence-specific DNA interactions by novel alkylating anthracycline derivatives.
1995 · S Marchini, O Gonzalez Paz, et al. · PubMed · 12
Works count: 31
Citation count: 1,871
H-index: 22
I10-index: 25
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