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Robert W. Kirby
Observed names:
R.W. Kirby,
Robert Kirby
Observed institutions:
Xention (United Kingdom),
Sheffield Hallam University
OpenAlex ID:
A5112933999
Effect of selective IK,ACh inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation
2020
·
Merle Friederike Fenner
, Helena Carstensen
, et al.
·
British Journal of Pharmacology
·
33
PDF
Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening
2016
·
Marc Rogers
, Nace Zidar
, et al.
·
Assay and Drug Development Technologies
·
25
PDF
Ligand- and Structure-Based Virtual Screening for Clathrodin-Derived Human Voltage-Gated Sodium Channel Modulators
2013
·
Tihomir Tomašić
, Basil Hartzoulakis
, et al.
·
Journal of Chemical Information and Modeling
·
16
Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels
2017
·
Nace Zidar
, Aleš Žula
, et al.
·
European Journal of Medicinal Chemistry
·
14
Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges
2013
·
Žiga Hodnik
, Tihomir Tomašić
, et al.
·
European Journal of Medicinal Chemistry
·
12
Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels
2014
·
Steve Peigneur
, Aleš Žula
, et al.
·
Marine Drugs
·
11
PDF
Large conductance Ca2+-activated K+ channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects
2013
·
R.W. Kirby
, A. Martelli
, et al.
·
Bioorganic & Medicinal Chemistry
·
9
Development of ASIC1a ligand-gated ion channel drug screening assays across multiple automated patch clamp platforms
2022
·
John Ridley
, Sam Manyweathers
, et al.
·
Frontiers in Molecular Neuroscience
·
8
PDF
Rubidium Efflux as a Tool for the Pharmacological Characterisation of Compounds with BK Channel Opening Properties
2008
·
Neil G. McKay
, Robert W. Kirby
, et al.
·
Methods in molecular biology
·
8
d-LysAsnProTyr tetrapeptide: a novel B-cell stimulant and stabilized bursin mimetic
2000
·
Lyne Gagnon
, Marika DiMarco
, et al.
·
Vaccine
·
8
New aryl and acylsulfonamides as state-dependent inhibitors of Nav1.3 voltage-gated sodium channel
2023
·
Nace Zidar
, Tihomir Tomašič
, et al.
·
European Journal of Medicinal Chemistry
·
7
PDF
The nucleobase guanine at the 3’-terminus of oligonucleotide RGLS4326 drives off-target AMPAR inhibition and CNS toxicity
2025
·
Tania Valencia
, Laura Y. Yen
, et al.
·
Nature Communications
·
4
PDF
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961]
2020
·
Bradley J. Ridder
, Derek J. Leishman
, et al.
·
Toxicology and Applied Pharmacology
·
2
PDF
Synthesis and biological evaluation of piperazine derivatives as novel isoform selective voltage-gated sodium (Nav) 1.3 channel modulators
2014
·
Marko Jukič
, Rok Frlan
, et al.
·
Medicinal Chemistry Research
·
2
Validation of an ASIC1a Ligand-Gated Assay on an Automated Patch Clamp Platform and its Use for Novel Ligand Screening
2021
·
Marc Rogers
, John Ridley
, et al.
·
Biophysical Journal
·
1
PDF
Time is a critical factor in evaluating indirect hERG inhibition by Oligonucleotide Therapeutics
2022
·
Yusheng Qu
, Robert Kirby
, et al.
PDF
The NaV1.5 late current in WT and Nav1.5-ΔKPQ mutant channels: An automated patch clamp LQT3 electrophysiological assay comparison
2021
·
Marc Rogers
, Maria G. Rotordam
, et al.
·
Journal of Pharmacological and Toxicological Methods
Predicting proarrhythmic risk exclusively using automated patch clamp data
2020
·
Edward Humphries
, John Ridley
, et al.
·
Journal of Pharmacological and Toxicological Methods
Using New In vitro Cardiac Ion Channel Assays and In Silico Models to Predict Proarrhythmic Risk with Automated Patch Clamp Data
2020
·
Edward S. Humphries
, John Ridley
, et al.
·
Biophysical Journal
PDF
New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment
2019
·
Edward S.A. Humphries
, Robert W. Kirby
, et al.
·
Journal of Pharmacological and Toxicological Methods
Assessment of human induced pluripotent stem-cell derived cardiomyocytes for evaluating drug induced arrhythmias with multi-electrode array
2019
·
Said El-Haou
, Robert W. Kirby
, et al.
·
Journal of Pharmacological and Toxicological Methods
CiPA Update: Refining In Vitro Cardiac Ion Channel Assays, In Silico Models and iPSC-Derived Cardiomyocyte Reagents for Improved Pro-arrhythmia Risk Prediction
2017
·
Marc Rogers
, Robert Kirby
, et al.
·
Journal of Pharmacological and Toxicological Methods
Developing a package of in vitro human cardiac ion channel assays to predict clinical arrhythmia risk
2016
·
Robert Kirby
, Raymond Tang
, et al.
·
Journal of Pharmacological and Toxicological Methods
Investigation of the pharmacophore of BK[ca] potassium channel openers.
2008
·
Robert W. Kirby
·
SHURA (Sheffield Hallam University Research Archive) (Sheffield Hallam University)
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Works count:
24
Citation count:
160
H-index:
8
I10-index:
6
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