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Matthieu Lepage
Institution:
Université de Sherbrooke
Observed institutions:
Université de Sherbrooke,
Institut de pharmacologie de Sherbrooke
ORCID:
0009-0004-4613-3906
Observed ORCID:
0009-0004-4613-3906
OpenAlex ID:
A5113295892
Works
8
Awards
1
From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants
2025
·
Gabriel Lemieux
, Jimena Pérez-Vargas
, et al.
·
Journal of Medicinal Chemistry
·
9
PDF
Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors
2025
·
Sára Ferková
, Matthieu Lepage
, et al.
·
European Journal of Medicinal Chemistry
·
9
Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket
2024
·
Michael Desgagné
, Antoine Désilets
, et al.
·
Journal of Medicinal Chemistry
·
9
PDF
Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
2025
·
Alexandre Joushomme
, Antoine Désilets
, et al.
·
Journal of Enzyme Inhibition and Medicinal Chemistry
·
6
Structural insights into frog skin-derived cyclic peptides as selective matriptase inhibitors
2025
·
Agata Gitlin-Domagalska
, Malihe Hassanzadeh
, et al.
·
European Journal of Medicinal Chemistry
·
1
TMPRSS6 Cleavage of β-Klotho Modulates FGF19 Signaling
2026
·
Matthieu Lepage
, Antoine Désilets
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6
2025
·
Walid Guerrab
, Matthieu Lepage
, et al.
·
Journal of Medicinal Chemistry
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Works count:
8
Citation count:
34
H-index:
4
I10-index:
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