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T. Hoffmann
Observed names:
Hoffmann, T.,
T HOFFMANN,
T Hoffmann
Observed institutions:
F. Hoffmann-La Roche AG,
Probiodrug (Germany),
Otto-von-Guericke-Universität Magdeburg
OpenAlex ID:
A5113580795
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
2002
·
M. B. Pepys
, J. Herbert
, et al.
·
Nature
·
539
Dipeptidyl peptidase IV (CD 26) and aminopeptidase N (CD 13) catalyzed hydrolysis of cytokines and peptides with N‐terminal cytokine sequences
1993
·
T. Hoffmann
, J. Faust
, et al.
·
FEBS Letters
·
118
PDF
Evidence for a crucial role of neutrophil‐derived serine proteases in the inactivation of interleukin‐6 at sites of inflammation
1999
·
U. Bank
, B. Küpper
, et al.
·
FEBS Letters
·
74
PDF
Substrate Specificity of Glutaminyl Cyclases from Plants and Animals
2003
·
S. Schilling
, S. Manhart
, et al.
·
Biological Chemistry
·
67
Simultaneous determination of incretin hormones and their truncated forms from human plasma by immunoprecipitation and liquid chromatography–mass spectrometry
2004
·
R WOLF
, T HOFFMANN
, et al.
·
Journal of Chromatography B
·
38
Characterisation of Human Dipeptidyl Peptidase IV Expressed in Pichia pastoris. A Structural and Mechanistic Comparison between the Recombinant Human and the Purified Porcine Enzyme
2003
·
J. Bär
, A. Weber
, et al.
·
Biological Chemistry
·
21
PP, PYY and NPY: Synthesis, Storage, Release and Degradation
2004
·
S. von Hörsten
, T. Hoffmann
, et al.
·
Handbook of experimental pharmacology
·
18
Evidence for an interaction between leptin, T cell costimulatory antigens CD28, CTLA-4 and CD26 (dipeptidyl peptidase IV) in BCG-induced immune responses of leptin- and leptin receptor-deficient mice
2004
·
J. Rüter
, T. Hoffmann
, et al.
·
Biological Chemistry
·
17
Improvement of glucose tolerance in Zucker diabetic fatty rats by long‐term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone
2004
·
E. Wargent
, C. Stocker
, et al.
·
Diabetes Obesity and Metabolism
·
15
DPP 4 Inhibitors increase differentially the expression of surfactant proteins in Fischer 344 rats
2014
·
A. Schmiedl
, D. Grützner
, et al.
·
Acta Physiologica
·
13
Characterization of RO4583298 as a novel potent, dual antagonist within vivoactivity at tachykinin NK1and NK3receptors
2010
·
P Malherbe
, F Knoflach
, et al.
·
British Journal of Pharmacology
·
12
PDF
Stress and Substance P but not the Substance P‐metabolite SP5‐11 trigger murine abortion by augmenting TNF‐α levels at the feto–maternal interface
2005
·
S. Fest
, A. C. Zenclussen
, et al.
·
Scandinavian Journal of Immunology
·
12
PDF
Abstract: P642 INHIBITION OF GLUTAMINYL CYCLASE ENHANCES INACTIVATION OF CCL2: A POTENTIAL THERAPY FOR CARDIOVASCULAR DISEASE
2009
·
H Cynis
, T Hoffmann
, et al.
·
Atherosclerosis Supplements
·
1
Preclinical studies to treat diabetes mellitus using novel DXM derivatives
2021
·
O Scholz
, S Otter
, et al.
·
Diabetologie und Stoffwechsel
Interrelationship between acinar zymogen activation, cell injury and inflammation in experimental acute pancreatitis
2013
·
W. Halangk
, T. Wartmann
, et al.
·
Pancreatology
Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro)
2005
·
M. Engel
, T. Hoffmann
, et al.
·
Worldwide Protein Data Bank
Porcine dipeptidyl peptidase IV (CD26) in complex with 7-Benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-purine-2,6-dione (BDPX)
2005
·
M. Engel
, T. Hoffmann
, et al.
·
Worldwide Protein Data Bank
Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-Gly-L-Pro-L-Ile (tBu-GPI)
2005
·
M. Engel
, T. Hoffmann
, et al.
·
Worldwide Protein Data Bank
Porcine dipeptidyl peptidase IV (CD26) in complex with 4-(2-Aminoethyl)-benzene sulphonyl fluoride (AEBSF)
2005
·
M. Engel
, T. Hoffmann
, et al.
·
Worldwide Protein Data Bank
Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor
2003
·
M. Engel
, T. Hoffmann
, et al.
·
Worldwide Protein Data Bank
Evidences for interleukin-6 (IL-6) — protease interactions in inflammation
1994
·
U. Bank
, T. Hoffmann
, et al.
·
Cytokine
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Works count:
22
Citation count:
945
H-index:
12
I10-index:
12
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