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Ryota Kunita

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
2005 · Shinji Hadano, Susanna C. Benn, et al. · Human Molecular Genetics · 138
Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
2010 · Shinji Hadano, Asako Otomo, et al. · PLoS ONE · 106
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The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis
2007 · Ryota Kunita, Asako Otomo, et al. · Journal of Biological Chemistry · 88
Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration
2007 · Shinji Hadano, Ryota Kunita, et al. · Neurochemistry International · 83
Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking
2004 · Ryota Kunita, Asako Otomo, et al. · Journal of Biological Chemistry · 68
Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation
2011 · Asako Otomo, Ryota Kunita, et al. · FEBS Letters · 50
Identification and localization of two genes on the chicken Z chromosome: implication of evolutionary conservation of the Z chromosome among avian species
1993 · Yasushi Saitoh, Akira Ogawa, et al. · Chromosome Research · 48
ALS2CL, the novel protein highly homologous to the carboxy‐terminal half of ALS2, binds to Rab5 and modulates endosome dynamics
2004 · Shinji Hadano, Asako Otomo, et al. · FEBS Letters · 42
ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth
2008 · Asako Otomo, Ryota Kunita, et al. · Biochemical and Biophysical Research Communications · 41
ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics
2007 · Kyoko Suzuki-Utsunomiya, Shinji Hadano, et al. · Biochemical and Biophysical Research Communications · 25
Identification and Characterization of Novel Members of the CREG Family, Putative Secreted Glycoproteins Expressed Specifically in Brain
2002 · Ryota Kunita, Asako Otomo, et al. · Genomics · 20
Predominant expression of a Z-chromosome-linked immunoglobulin superfamily gene, ZOV3, in steroidogenic cells of ovarian follicles and in embryonic gonads of chickens
1997 · Ryota Kunita, Osamu Nakabayashi, et al. · Differentiation · 18
Molecular cloning of acid α-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quails
1997 · Ryota Kunita, Osamu Nakabayashi, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 16
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Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice
2010 · Shinji Hadano, Yasuhiro Yoshii, et al. · Neuroscience Research · 15
Sex-Specific DNA Sequences in Galliformes and Their Application to the Study of Sex Differentiation
2019 · Shigeki Mizuno, Yasushi Saitoh, et al. · CRC Press eBooks · 4
Disturbance of endolysosomal protein degradation underlies the pathogenesis of ALS2-linked motor neuron diseases
2010 · Shinji Hadano, Asako Otomo, et al. · Neuroscience Research
Works count: 18
Citation count: 762
H-index: 14
I10-index: 14
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