Author

Darren R. Shafren

Observed names: D R Shafren, D. R. Shafren, D. Shafren, D.R. SHAFREN, D.R. Shafren, Darren R Shafren, Darren R. SHAFREN, Darren Shafren

Observed institutions: John Hunter Hospital, Hunter Medical Research Institute, John Hunter Children's Hospital, Viralytics Limited (Australia), University of Newcastle Australia, Newcastle University

OpenAlex ID: A5113715397

Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment

1995 · D R Shafren, R C Bates, et al. · Journal of Virology · 291

Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry

1997 · D R Shafren, D J Dorahy, et al. · Journal of Virology · 243

Interleukin-10 Gene Expression in Acute Virus-induced Asthma

2005 · Terry V. Grissell, Heather Powell, et al. · American Journal of Respiratory and Critical Care Medicine · 199

Systemic Therapy of Malignant Human Melanoma Tumors by a Common Cold-Producing Enterovirus, Coxsackievirus A21

2004 · Darren R. Shafren, Gough G. Au, et al. · Clinical Cancer Research · 154

A decay-accelerating factor-binding strain of coxsackievirus B3 requires the coxsackievirus-adenovirus receptor protein to mediate lytic infection of rhabdomyosarcoma cells

1997 · D R Shafren, D T Williams, et al. · Journal of Virology · 126

Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer

2019 · Nicola E. Annels, David Mansfield, et al. · Clinical Cancer Research · 122

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Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma

2007 · Gough G. Au, Lisa F. Lincz, et al. · British Journal of Haematology · 99

The Integrins α3β1 and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

2000 · Rick F. Thorne, John F. Marshall, et al. · Journal of Biological Chemistry · 90

Oncolysis of vascular malignant human melanoma tumors by Coxsackievirus A21

2005 · Gough Au, A. Lindberg, et al. · International Journal of Oncology · 83

Systemic targeting of metastatic human breast tumor xenografts by Coxsackievirus A21

2008 · Kathryn A. Skelding, Richard D. Barry, et al. · Breast Cancer Research and Treatment · 72

Mouse cells expressing human intercellular adhesion molecule-1 are susceptible to infection by coxsackievirus A21

1997 · D R Shafren, D J Dorahy, et al. · Journal of Virology · 72

Final data from CALM: A phase II study of Coxsackievirus A21 (CVA21) oncolytic virus immunotherapy in patients with advanced melanoma.

2015 · Robert Hans Ingemar Andtbacka, Brendan D. Curti, et al. · Journal of Clinical Oncology · 69

Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus

2018 · Nicola E. Annels, Mehreen Arif, et al. · Molecular Therapy — Oncolytics · 64

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Oncolysis of human ovarian cancers by echovirus type 1

2005 · Darren R. Shafren, Dianne Sylvester, et al. · International Journal of Cancer · 53

Cellular receptor interactions of C-cluster human group A coxsackieviruses

2003 · Nicole G. Newcombe, Per Andersson, et al. · Journal of General Virology · 52

Molecular characterization of M1146, an American isolate of Ljungan virus (LV) reveals the presence of a new LV genotype

2003 · E. Susanne Johansson, Bo Niklasson, et al. · Journal of General Virology · 52

Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor

1998 · Darren R. Shafren · Journal of Virology · 52

A phase 1b single-arm trial of intratumoral oncolytic virus V937 in combination with pembrolizumab in patients with advanced melanoma: results from the CAPRA study

2022 · Ann W. Silk, Steven J. O’Day, et al. · Cancer Immunology Immunotherapy · 48

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Potent Oncolytic activity of human enteroviruses against human prostate cancer

2008 · Linda J. Berry, Gough G. Au, et al. · The Prostate · 46

Avian encephalomyelitis: A review

1994 · G. A. Tannock, D. R. Shafren · Avian Pathology · 46

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CD36 Forms Covalently Associated Dimers and Multimers in Platelets and Transfected COS-7 Cells

1997 · Rick F. Thorne, Clifford J. Meldrum, et al. · Biochemical and Biophysical Research Communications · 45

Integrin αvβ6 Enhances Coxsackievirus B1 Lytic Infection of Human Colon Cancer Cells

1997 · Michael V. Agrez, Darren R. Shafren, et al. · Virology · 43

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Enhanced oncolysis mediated by Coxsackievirus A21 in combination with doxorubicin hydrochloride

2010 · Kathryn A. Skelding, Richard D. Barry, et al. · Investigational New Drugs · 42

Validity of the Common Cold Questionnaire (CCQ) in Asthma Exacerbations

2008 · Heather Powell, Joanne Smart, et al. · PLoS ONE · 40

Abstract CT026: Phase 1b study of intratumoral Coxsackievirus A21 ( C V A 21) and systemic p emb r olizumab in a dvanced melanoma patients: Interim results of the CAPRA clinical trial

2017 · Ann W. Silk, Howard Kaufman, et al. · Cancer Research · 36

Works count: 96

Citation count: 2,955

H-index: 29

I10-index: 54