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Keith Wilcoxen

Observed names: K. M. WILCOXEN, K. WILCOXEN, K. Wilcoxen, K.M. Wilcoxen, Keith M Wilcoxen, Keith M. Wilcoxen, Keith Matthew Wilcoxen, Wilcoxen Keith, Wilcoxen, K.M.
Observed institutions: Northwestern University, Scripps Research Institute, Tesaro (United States), Eisai (United States), Boston Pharmaceuticals (United States), Neurocrine Biosciences (United States)
OpenAlex ID: A5113792391
Antibacterial agents based on the cyclic d,l-α-peptide architecture
2001 · Sara Fernandez-Lopez, Hui-Sun Kim, et al. · Nature · 938
Niraparib: A Poly(ADP-ribose) Polymerase (PARP) Inhibitor for the Treatment of Tumors with Defective Homologous Recombination
2015 · Philip Jones, Keith Wilcoxen, et al. · Journal of Medicinal Chemistry · 183
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity
2022 · Rachid Essalmani, Jaspreet Jain, et al. · Journal of Virology · 179
Antiviral cyclic d,l-α-peptides: Targeting a general biochemical pathway in virus infections
2005 · W. Seth Horne, Christopher M. Wiethoff, et al. · Bioorganic & Medicinal Chemistry · 129
Design of 2,5-Dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and Structure−Activity Relationships of a Series of Potent and Orally Active Corticotropin-Releasing Factor Receptor Antagonists
2004 · Chen, Keith M. Wilcoxen, et al. · Journal of Medicinal Chemistry · 116
Coupling of 2-Substituted 1-Fluorovinylstannanes with Organic Halides Catalyzed by Palladium(0)/Copper(I) Iodide. A Mild and Stereospecific Method to Monofluoroolefins
1999 · Chen, Keith Wilcoxen, et al. · The Journal of Organic Chemistry · 81
In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma
2016 · Mariam M. AlHilli, Marc A. Becker, et al. · Gynecologic Oncology · 73
Recent Advances of MEK Inhibitors and Their Clinical Progress
2007 · Wang John (Yuan), Wilcoxen Keith, et al. · Current Topics in Medicinal Chemistry · 73
Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition
2017 · Gayathri Srinivasan, Gurjit Singh Sidhu, et al. · Cancer Chemotherapy and Pharmacology · 60
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Automated Mass Spectrometric Sequence Determination of Cyclic Peptide Library Members
2002 · James E. Redman, Keith M. Wilcoxen, et al. · Journal of Combinatorial Chemistry · 59
New methods for the synthesis of fluoroolefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes and organostannanes
2000 · Chen Chen, Keith Wilcoxen, et al. · Journal of Fluorine Chemistry · 50
Synthesis of fluorinated olefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes
1999 · Chen Chen, Keith Wilcoxen, et al. · Tetrahedron Letters · 49
Palladium/Copper (I) halide-cocatalyzed stereospecific coupling of 1-fluorovinylstannanes with aryl iodides and acyl chlorides
1997 · Chen Chen, Keith Wilcoxen, et al. · Tetrahedron Letters · 42
Discovery of TSR-022, a novel, potent anti-human TIM-3 therapeutic antibody
2016 · A. Murtaza, H. Laken, et al. · European Journal of Cancer · 34
Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5-a]pyrimidines as potent CRF1 receptor antagonists
2004 · Charles Q Huang, Keith M Wilcoxen, et al. · Bioorganic & Medicinal Chemistry Letters · 34
Biomimetic Catalysis of Intermodular Aminoacyl Transfer
2007 · Keith M. Wilcoxen, Luke J. Leman, et al. · Journal of the American Chemical Society · 31
Synthesis and initial structure–Activity relationships of a novel series of imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists
2002 · Keith M. Wilcoxen, Yun-Fei Zhu, et al. · Bioorganic & Medicinal Chemistry Letters · 31
A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease
2022 · Lisa E.J. Douglas, James A. Reihill, et al. · Cell chemical biology · 30
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Practical metabolomics in drug discovery
2010 · Keith M Wilcoxen, Taisuke Uehara, et al. · Expert Opinion on Drug Discovery · 30
N-aroyloxy-2-thiopyridones as efficient oxygen-radical generators: novel time-controlled DNA photocleaving reagents
1996 · Emmanuel A. Theodorakis, Keith M. Wilcoxen · Chemical Communications · 29
Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme
2021 · Matthew M. Hamilton, Faika Mseeh, et al. · Journal of Medicinal Chemistry · 28
Initial Structure–Activity Relationship Studies of a Novel Series of Pyrrolo[1,2-a]pyrimid-7-ones as GnRH Receptor Antagonists
2002 · Yun-Fei Zhu, R.Scott Struthers, et al. · Bioorganic & Medicinal Chemistry Letters · 28
Erratum: correction: Antibacterial agents based on the cyclic d,l-α-peptide architecture
2001 · Sara Fernandez-Lopez, Hui-Sun Kim, et al. · Nature · 28
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Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts
2018 · Ádám Póti, Kinga Berta, et al. · British Journal of Cancer · 27
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Optimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility
2004 · Chen Chen, Keith M Wilcoxen, et al. · Bioorganic & Medicinal Chemistry Letters · 27
Works count: 88
Citation count: 2,818
H-index: 25
I10-index: 46
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