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Hina Sarfraz
Institutions:
Quaid-i-Azam University,
Hong Kong University of Science and Technology
Observed institutions:
Quaid-i-Azam University,
COMSATS University Islamabad,
Hong Kong University of Science and Technology
ORCID:
0009-0003-9480-2986
Observed ORCIDs:
0009-0003-9480-2986,
0009-0002-1497-8096
OpenAlex ID:
A5116442323
Synthesis, biological screening and computational analysis of Thiazole linked Thiazolidinone Schiff bases as anti-Alzheimer's drug candidates
2025
·
Thoraya A. Farghaly
, Wajid Rehman
, et al.
·
Bioorganic Chemistry
·
20
Facile indazole-endowed thiadiazole hybrid derivatives as antibacterial, anti-diabetic and thymidine phosphorylase inhibitors: An insight to experimental, in-vitro biological potential and computational approaches
2025
·
Sabeen Arshad
, Aneela Maalik
, et al.
·
Saudi Pharmaceutical Journal
·
20
PDF
Design, synthesis and biological profiling of bis-thiazole linked Schiff bases as effective enzyme inhibitors for targeting urease and thymidine phosphorylase proteins
2026
·
Yousaf Khan
, Hina Sarfraz
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
16
Discovery and optimization of a novel series of pyrazole-linked oxadiazole conjugates as α-amylase inhibitors: In-silico DFT, ADMET-prediction, Toxicological assessment and Molecular docking insight
2025
·
Hina Sarfraz
, Wajid Rehman
, et al.
·
Journal of Molecular Structure
·
15
Medicinal approaches toward diabetes mellitus based on chloro-1H-indazole-derived triazolo-thiadiazole hybrid derivatives: design, synthesis, characterization, in vitro and in silico insights
2025
·
Yousaf Khan
, Shoaib Khan
, et al.
·
Journal of the Iranian Chemical Society
·
14
Synthesis and computational studies on novel thiazine-thiazole hybrid analogues as dual α-amylase and α-glucosidase inhibitors for combating diabetes mellitus
2025
·
Wajid Rehman
, Yousaf Khan
, et al.
·
Computational Biology and Chemistry
·
13
Facile 3-chloro-1H-indazole based 1,3,4-thiadiazole derivatives as novel thymidine phosphorylase and anti-diabetic inhibitors: Experimental, in-vitro and molecular modelling approaches
2025
·
Yousaf Khan
, Aneela Maalik
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
12
Unveiling of the novel benzothiazole derived thiazolidinone derivatives: in vitro and in silico insights to design a promising agent for anti-Alzheimer’s disease
2025
·
Yousaf Khan
, Anila Mukhtiar
, et al.
·
Zeitschrift für Naturforschung C
·
12
Innovative Horizons in Drug Design: Exploring the Synthesis and Medicinal Properties of Heterocyclic Schiff Bases. A Review
2025
·
Yousaf Khan
, Hina Sarfraz
, et al.
·
Mini-Reviews in Medicinal Chemistry
·
12
Scaffold hopping strategy toward novel Pyrazolo[3,4-d]pyrimidine-based thiazole frameworks as potential cholinesterase inhibitors for treating Alzheimer’s disease: insight into in vitro and in silico approaches
2026
·
Fakhria A. Al-Joufi
, Maher S. Alwethaynani
, et al.
·
Journal of Molecular Structure
·
8
Integrating kinetic mechanism of novel benzimidazole derivatives as potential acetylcholinesterase inhibitors: Insight into in-vitro and in-silico approaches
2025
·
Moh Tariq
, Rafaqat Hussain
, et al.
·
Journal of Molecular Structure
·
7
Investigation of In-silico DFT, ADMET Prediction and Molecular Docking Insight: Synthesis and in-vitro α-Amylase Activity of Novel Benzoxazole and Benzothiazole Scaffolds
2025
·
Asma Sardar
, Hina Sarfraz
, et al.
·
Journal of Computational Biophysics and Chemistry
·
5
In Vitro Biological Screening and In Silico Molecular Modeling Studies of Thiadiazole-Bearing Benzoxazole Derivatives as Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors
2025
·
Asma Sardar
, Rafaqat Hussain
, et al.
·
Journal of Computational Biophysics and Chemistry
·
4
Structure-guided optimization of N-(5-((2-oxopropyl) thio)-1,3,4-thiadiazol-2-yl) propionamide frameworks as potent SARS-CoV-2 Mpro inhibitor for treating coronavirus disease
2026
·
Maher S. Alwethaynani
, Reem Nabil Hassan
, et al.
·
Bioorganic Chemistry
·
3
Optimization of 1-(Difluoromethyl)-6-(1H2 Imidazol-5-yl) Imidazo[1,5-a] Pyrazin-8(7H)-One Frameworks as Promising Cholinesterase Inhibitors for Treating Alzheimer’s Disease
2026
·
Hanan M. Alharbi
, Nawal Al-Hoshani
, et al.
·
Journal of Computational Biophysics and Chemistry
·
3
Carbon–carbon bond formation reaction overactive sites of heterogeneous catalysts: understanding the role of catalytic sites with reaction mechanism, performance, stability, and product selectivity
2025
·
Hina Sarfraz
, Saleh Shabanian
, et al.
·
Pure and Applied Chemistry
·
3
In-Silico DFT, ADMET Prediction, Toxicological Assessment and Molecular Modeling Studies of Hydrazone-Derived Thiazolidinone Derivatives: Insight into In-vitro Urease Activity, and Kinetic Mechanism Investigations
2025
·
Asma Sardar
, Rafaqat Hussain
, et al.
·
Journal of Computational Biophysics and Chemistry
·
3
Integrating Computational and Experimental Approaches to Identify Novel Pyrazolo[3,4-d]pyrimidine-containing Thiadiazole Frameworks for Treating Alzheimer’s Disease
2026
·
Hanan M. Alharbi
, Nawal Al-Hoshani
, et al.
·
Journal of Computational Biophysics and Chemistry
·
2
Optimization of 7H-Pyrrolo[2,3-d]pyrimidine-containing thiazole frameworks as potential anti-proliferative agents: A combined in-vitro and in-silico investigations
2026
·
Hina Sarfraz
, Rafaqat Hussain
, et al.
·
Journal of Molecular Structure
·
2
Rational-guided design and optimization of 6-fluoro-4-(trifluoromethyl)benzofuran-based thiazole derivatives as potent methionine adenosyltransferase 2A inhibitors: In vitro and In silico approaches
2026
·
Fakhria A. Al-Joufi
, Hina Sarfraz
, et al.
·
Journal of Molecular Structure
·
2
Multiparameter optimization of broad-spectrum thymidine phosphorylase inhibition, ADMET properties, molecular docking, and DFT screening of novel pyrazole-based thiadiazole/thiazole derivatives
2026
·
Reem Nabil Hassan
, Hina Sarfraz
, et al.
·
Zeitschrift für Naturforschung C
·
2
Investigation of Parkinson’s Disease: Synthesis, In Vitro and In Silico Screening of Imidazopyridine-Derived Thiadiazole-Bearing Benzimidazole Scaffolds as Effective MAO-A and MAO-B Inhibitors
2025
·
Mariam Abdulaziz Alkhateeb
, Rafaqat Hussain
, et al.
·
Journal of Computational Biophysics and Chemistry
·
2
Structure activity relationship-guided scaffold hopping for identification of novel thiadiazole derivatives as potent SARS-CoV-2 Mpro inhibitors
2026
·
Maher S. Alwethaynani
, Khaled Alzhrani
, et al.
·
Zeitschrift für Naturforschung C
·
1
Investigation of Pyrazole-Linked Carbonitrile-Based Schiff Bases through Molecular Dynamic Simulation As Promising Urease and Thymidine Phosphorylase Inhibitors: Synthesis in vitro Biological Screening, DFT and Computational Approaches
2026
·
Hina Sarfraz
, Yousaf Khan
, et al.
·
Journal of Computational Biophysics and Chemistry
·
1
Discovery of Novel 1,3,4-oxadiazole-based Inhibitors Against Urease and Diabetes: Design, Synthesis, SAR, Biological, and Molecular Docking Screening
2025
·
Sabeen Arshad
, Aneela Maalik
, et al.
·
Medicinal Chemistry
·
1
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Works count:
45
Citation count:
185
H-index:
9
I10-index:
9
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