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Andrew J. Haak
Observed names:
A J Haak,
A. Haak,
A.J. Haak,
Andrew Haak,
Andrew J Haak,
Haak, Andrew,
Haak, Andrew J.
show all 7
Institution:
Mayo Clinic
Observed institutions:
Mayo Clinic,
Minnesota State University Moorhead,
University of Michigan,
Michigan Medicine,
University of Minnesota Rochester,
North Dakota State University,
Michigan State University
show all 7
ORCID:
0000-0002-5323-253X
Observed ORCID:
0000-0002-5323-253X
OpenAlex ID:
A5064053749
Cellular senescence mediates fibrotic pulmonary disease
2017
·
Marissa J. Schafer
, Thomas A. White
, et al.
·
Nature Communications
·
1,609
PDF
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis
2019
·
Andrew J. Haak
, Enis Kostallari
, et al.
·
Science Translational Medicine
·
219
Novel Rho/MRTF/SRF Inhibitors Block Matrix-stiffness and TGF-β–Induced Fibrogenesis in Human Colonic Myofibroblasts
2013
·
Laura A. Johnson
, Eva S. Rodansky
, et al.
·
Inflammatory Bowel Diseases
·
197
PDF
Aging and anatomical variations in lung tissue stiffness
2018
·
Delphine Sicard
, Andrew J. Haak
, et al.
·
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
172
PDF
Targeting the Myofibroblast Genetic Switch: Inhibitors of Myocardin-Related Transcription Factor/Serum Response Factor–Regulated Gene Transcription Prevent Fibrosis in a Murine Model of Skin Injury
2014
·
Andrew J. Haak
, Pei-Suen Tsou
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
103
PDF
Targeting Senescent Cells in Fibrosis: Pathology, Paradox, and Practical Considerations
2018
·
Marissa J. Schafer
, Andrew J. Haak
, et al.
·
Current Rheumatology Reports
·
102
PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state
2019
·
Nunzia Caporarello
, Jeffrey A Meridew
, et al.
·
Thorax
·
95
PDF
Matrix biomechanics and dynamics in pulmonary fibrosis
2017
·
Andrew J. Haak
, Qi Tan
, et al.
·
Matrix Biology
·
95
CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis
2019
·
Giovanni Ligresti
, Nunzia Caporarello
, et al.
·
JCI Insight
·
92
Cellular Mechanisms of Tissue Fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription
2014
·
Pei-Suen Tsou
, Andrew J. Haak
, et al.
·
American Journal of Physiology-Cell Physiology
·
84
Vascular dysfunction in aged mice contributes to persistent lung fibrosis
2020
·
Nunzia Caporarello
, Jeffrey A. Meridew
, et al.
·
Aging Cell
·
78
PDF
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression
2019
·
Dakota L. Jones
, Andrew J. Haak
, et al.
·
Journal of Cell Science
·
75
Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents
2013
·
Jessica L. Bell
, Andrew J. Haak
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
68
Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies
2020
·
Andrew J. Haak
, Merrick T. Ducharme
, et al.
·
Trends in Pharmacological Sciences
·
65
RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation
2018
·
Raymond S. Oh
, Andrew J. Haak
, et al.
·
Journal of Cell Science
·
56
Nascent Lung Organoids Reveal Epithelium- and Bone Morphogenetic Protein–mediated Suppression of Fibroblast Activation
2019
·
Qi Tan
, Xiao Yin Ma
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
45
Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma
2016
·
Andrew J. Haak
, Kathryn M. Appleton
, et al.
·
Molecular Cancer Therapeutics
·
45
Combined control of the fibroblast contractile program by YAP and TAZ
2021
·
Patrick A. Link
, Kyoung Moo Choi
, et al.
·
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
42
Precision-Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research: An Official American Thoracic Society Workshop Report
2024
·
Mareike Lehmann
, Ramaswamy Krishnan
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
41
5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma
2019
·
Dylan J. Kahl
, Kim M. Hutchings
, et al.
·
Journal of Medicinal Chemistry
·
41
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation
2020
·
Aja Aravamudhan
, Andrew J. Haak
, et al.
·
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
39
IL-23R is a senescence-linked circulating and tissue biomarker of aging
2024
·
Chase M. Carver
, Sonia L. Rodriguez
, et al.
·
Nature Aging
·
37
PDF
microRNA overexpression in slow transit constipation leads to reduced Na V 1.5 current and altered smooth muscle contractility
2019
·
Amelia Mazzone
, Peter R Strege
, et al.
·
Gut
·
34
PDF
GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
2021
·
Kyoung Moo Choi
, Andrew J. Haak
, et al.
·
Journal of Cellular Physiology
·
27
YAP/TAZ are Activated by Mechanical and Hormonal Stimuli in Myometrium and Exhibit Increased Baseline Activation in Uterine Fibroids
2020
·
MacKenzie P. Purdy
, Merrick Ducharme
, et al.
·
Reproductive Sciences
·
27
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Works count:
85
Citation count:
3,732
H-index:
25
I10-index:
37
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