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Grace Ann

Observed name: Ann, Grace
OpenAlex ID: A5137793383
The Selenium Gap in Controlled Environment Agriculture: Why Aquaponic and Hydroponic Food Systems May Amplify Population Selenium Deficiency Without Awareness or Regulation
2026 · Ann, Grace, Ann, Grace · Figshare
The Leiomyoma-LAM Convergence: Nrf2-Keap1-Cullin 3 Axis Hijacking, Selenium-Dependent GPx Exhaustion, and a Three-Tier Metabolic Governance Strategy Across Estrogen-Sensitive and mTOR-Driven Smooth Muscle Proliferation
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Hashimoto's Triple Gate: Selenium Deficiency, Iron-Dependent TPO Failure, and H. pylori-Mediated Autoimmune Triggering as Three Independent Upstream Failures in Hashimoto's Thyroiditis
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Ergothioneine and Renal Mitochondrial Protection: OCTN1-Mediated Accumulation in Proximal Tubular Cells as a Parallel and Non-Redundant Antioxidant Defense Alongside GPx3 in the Selenoprotein Axis Framework
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
A Proposed Randomized Controlled Trial Design: Testing Coordinated Selenoprotein Axis Restoration with Autonomic Gate Intervention in Chronically Stressed, Selenium-Insufficient Adults — Protocol for the SIK-STRESS Trial
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Ergothioneine and Renal Mitochondrial Protection: OCTN1-Mediated Accumulation in Proximal Tubular Cells as a Parallel and Non-Redundant Antioxidant Defense Alongside GPx3 in the Selenoprotein Axis Framework
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
GLP-1 Receptor Agonism and the Selenoprotein Axis: Why the Kidney-Protective Mechanism of Semaglutide Is Selenium-Gated — NRF2 Activation Without Selenocysteine Substrate Cannot Complete the Selenoprotein Expression Program — Including Bone Health Addendum
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Vitamin D-NRF2-Selenium Triple Deficiency: Convergent Antioxidant System Failure Through Three Independent Upstream Deficiencies Governing the Same Downstream Selenoprotein Expression Program
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Gut-Selenium-Thyroid Axis: Microbiome-Dependent Selenium Biotransformation, Bacterial Deiodinase Activity, and Dysbiosis as a Third Route to SIK Axis Failure Independent of Dietary Selenium or Iodine Status
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
GLP-1 Receptor Agonism and the Selenoprotein Axis: Why the Kidney-Protective Mechanism of Semaglutide Is Selenium-Gated — NRF2 Activation Without Selenocysteine Substrate Cannot Complete the Selenoprotein Expression Program — Including Bone Health Addendum
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Vitamin D-NRF2-Selenium Triple Deficiency: Convergent Antioxidant System Failure Through Three Independent Upstream Deficiencies Governing the Same Downstream Selenoprotein Expression Program
2026 · Ann, Grace, Ann, Grace · Figshare
Long COVID, ME/CFS, and the Selenoprotein Axis: Post-Viral Selenoprotein Depletion, GPx4-Mediated Lipid Oxidative Damage, and CoQ10 Deficiency as Convergent Mechanisms of Persistent Fatigue
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The SIK Axis and Cardiovascular Disease: Selenium-Dependent Selenoproteins, CoQ10-FSP1 Anti-Ferroptotic Defense, and T3-Mediated Coronary Vasodilation as Three Convergent Determinants of Cardiac Mitochondrial Protection
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
A Proposed Randomized Controlled Trial Design: Testing Coordinated Selenoprotein Axis Restoration with Autonomic Gate Intervention in Chronically Stressed, Selenium-Insufficient Adults — Protocol for the SIK-STRESS Trial
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Long COVID, ME/CFS, and the Selenoprotein Axis: Post-Viral Selenoprotein Depletion, GPx4-Mediated Lipid Oxidative Damage, and CoQ10 Deficiency as Convergent Mechanisms of Persistent Fatigue
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Ferroptosis as the Universal Selenoprotein Axis Failure Mechanism: GPx4-Selenium and FSP1-CoQ10 as Two Complementary Anti-Ferroptotic Defense Systems Across Multiple Organ Systems
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Autonomic Gate: Chronic HPA Dysregulation, Vagal Tone Reduction, and Circadian GPx Suppression as a Seventh Upstream Failure Mode in the Selenoprotein Axis
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
A Proposed Selenium Deficiency Staging Framework: SELENOP-Guided Clinical Staging of Selenoprotein Reserve Depletion Across High-Metabolic End-Artery Tissues — From Subclinical to Multi-Organ Vulnerability
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Autonomic Gate: Chronic HPA Dysregulation, Vagal Tone Reduction, and Circadian GPx Suppression as a Seventh Upstream Failure Mode in the Selenoprotein Axis
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Mast Cell Activation Syndrome and the Selenoprotein Axis: Ferroptosis-Driven Mast Cell Hyperreactivity, GPx4 Depletion as an Upstream Driver of MCAS, and Selenium as a Direct Mast Cell Stabilizer
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
A Proposed Selenium Deficiency Staging Framework: SELENOP-Guided Clinical Staging of Selenoprotein Reserve Depletion Across High-Metabolic End-Artery Tissues — From Subclinical to Multi-Organ Vulnerability
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Hyperuricemia as a Ninth Upstream Gate in the Selenoprotein Axis: Uric Acid-Mediated NRF2 Suppression, RAGE-NF-κB Hepcidin Amplification, and Ferroptosis-Driven Hyperuricemic Nephropathy as Three Convergent Mechanisms Connecting Gout to the Selenoprotein Axis Framework
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Vitamin D-NRF2-Selenium Triple Deficiency: Convergent Antioxidant System Failure Through Three Independent Upstream Deficiencies Governing the Same Downstream Selenoprotein Expression Program
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Mast Cell Activation Syndrome and the Selenoprotein Axis: Ferroptosis-Driven Mast Cell Hyperreactivity, GPx4 Depletion as an Upstream Driver of MCAS, and Selenium as a Direct Mast Cell Stabilizer
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
The Hashimoto's Triple Gate: Selenium Deficiency, Iron-Dependent TPO Failure, and H. pylori-Mediated Autoimmune Triggering as Three Independent Upstream Failures in Hashimoto's Thyroiditis
2026 · Ann, Grace · Zenodo (CERN European Organization for Nuclear Research)
Works count: 43
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