Author

Vijay K. Gombar

Observed names: Gombar, Vijay, Gombar, Vijay K., V Gombar, V K Gombar, V. Gombar, V. K. GOMBAR, V. K. Gombar, V.K Gombar, V.K. Gombar, VK Gombar, Vijay Gombar, Vijay K Gombar, Vijay K. Gombar

Observed institutions: University of North Carolina at Chapel Hill, Pennsylvania State University, Eli Lilly (United States), GlaxoSmithKline (United States), Panjab University, Simulations Plus (United States)

ORCID: 0000-0002-2803-8591

Observed ORCID: 0000-0002-2803-8591

OpenAlex ID: A5071768014

The Importance of Being Earnest: Validation is the Absolute Essential for Successful Application and Interpretation of QSPR Models

2003 · Alexander Tropsha, Paola Gramatica, et al. · QSAR & Combinatorial Science · 2,186

Development and Validation of k-Nearest-Neighbor QSPR Models of Metabolic Stability of Drug Candidates

2003 · Min Shen, Yunde Xiao, et al. · Journal of Medicinal Chemistry · 183

Predicting P-glycoprotein substrates by a quantitative structure–activity relationship model

2004 · Vijay K. Gombar, Joseph W. Polli, et al. · Journal of Pharmaceutical Sciences · 112

Assessment of n-Octanol/Water Partition Coefficient: When Is the Assessment Reliable?

1996 · Vijay K. Gombar, Kurt Enslein · Journal of Chemical Information and Computer Sciences · 89

Quantitative Structure–Activity Relationship Models of Clinical Pharmacokinetics: Clearance and Volume of Distribution

2013 · Vijay K. Gombar, Stephen D. Hall · Journal of Chemical Information and Modeling · 81

Role of ADME Characteristics in Drug Discovery and Their In Silico Evaluation: In Silico Screening of Chemicals for their Metabolic Stability

2003 · Vijay Gombar, Ivin Silver, et al. · Current Topics in Medicinal Chemistry · 80

Modeling ADMET

2016 · Jayeeta Ghosh, Michael S. Lawless, et al. · Methods in molecular biology · 59

Assessment of effect levels of chemicals from quantitative structure-activity relationship (QSAR) models. I. Chronic lowest-observed-adverse-effect level (LOAEL)

1995 · M.M. Mumtaz, L.A. Knauf, et al. · Toxicology Letters · 52

A quantitative structure-toxicity relationships model for the dermal sensitization guinea pig maximization assay

1997 · K Enslein, V.K Gombar, et al. · Food and Chemical Toxicology · 48

An evaluation of in-house and off-the-shelf in silico models: Implications on guidance for mutagenicity assessment

2015 · Robert Jolly, Kausar Begam Riaz Ahmed, et al. · Regulatory Toxicology and Pharmacology · 41

Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models

2010 · Patricia Ruiz, Moiz Mumtaz, et al. · Toxicology and Applied Pharmacology · 39

In silico approaches to predicting cancer potency for risk assessment of genotoxic impurities in drug substances

2010 · Joel P. Bercu, Stuart M. Morton, et al. · Regulatory Toxicology and Pharmacology · 39

Metabolic‐intermediate complex formation with cytochrome P450: Theoretical studies in elucidating the reaction pathway for the generation of reactive nitroso intermediate

2012 · Nikhil Taxak, Prashant V. Desai, et al. · Journal of Computational Chemistry · 38

Mixture deconvolution and analysis of Ames mutagenicity data

2002 · S.Stanley Young, Vijay K Gombar, et al. · Chemometrics and Intelligent Laboratory Systems · 37

Saagar–A New, Extensible Set of Molecular Substructures for QSAR/QSPR and Read-Across Predictions

2020 · Alexander Y. Sedykh, Ruchir R. Shah, et al. · Chemical Research in Toxicology · 34

Release characteristics of some bronchodilators from compressed hydrophilic polymeric matrices and their correlation with molecular geometry

1988 · S.K. Baveja, K.V. Ranga Rao, et al. · International Journal of Pharmaceutics · 31

Salmonella mutagenicity and rodent carcinogenicity: Quantitative structure-activity relationships

1990 · Benjamin W. Blake, Kurt Enslein, et al. · Mutation Research/Genetic Toxicology · 27

A Structure-Biodegradability Relationship Model by Discriminant Analysis

1991 · Vijay K. Gombar, Kurt Enslein · Euro courses. Chemical and environmental science · 25

A QSAR Model of Teratogenesis

1991 · Vijay K. Gombar, Harold H. Borgstedt, et al. · Quantitative Structure-Activity Relationships · 25

Reliable Assessment of Log P of Compounds of Pharmaceutical Relevance

1999 · V. K. Gombar · SAR and QSAR in environmental research · 23

Quantitative Structure‐Activity Relationship (QSAR) Studies Using Electronic Descriptors Calculated from Topological and Molecular Orbital (MO) Methods

1990 · Vijay K. Gombar, Kurt Enslein · Quantitative Structure-Activity Relationships · 23

Characterizing PFAS hazards and risks: a human population-based in vitro cardiotoxicity assessment strategy

2024 · Lucie C. Ford, Hsing-Chieh Lin, et al. · Human Genomics · 17

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Computational Approaches for Assessment of Toxicity: A Historical Perspective and Current Status

2006 · Vijay K. Gombar, Brian E. Mattioni, et al. · Computational Toxicology · 15

Carcinogenicity of azathioprine: An S-AR investigation

1993 · Vijay K. Gombar, Kurt Einstein, et al. · Mutation Research Letters · 11

Correlation between topological features and molar volumes of n-alkanes and excess volumes of their binary mixtures

1979 · Dharam V. S. Jain, Vijay K. Gombar · Journal of the Chemical Society Faraday Transactions 1 Physical Chemistry in Condensed Phases · 10

Works count: 104

Citation count: 3,393

H-index: 21

I10-index: 25