Get started
Author

Shih-Yu Chen

Highly multiplexed simultaneous detection of RNAs and proteins in single cells
2016 · Andreas P Frei, Felice-Alessio Bava, et al. · Nature Methods · 325
Spatial multi-omics analyses of the tumor immune microenvironment
2022 · Wan-Chen Hsieh, Bugi Ratno Budiarto, et al. · Journal of Biomedical Science · 217
PDF
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis
2018 · Jared M. Churko, Priyanka Garg, et al. · Nature Communications · 207
PDF
Unifying mechanism for different fibrotic diseases
2017 · Gerlinde Wernig, Shih-Yu Chen, et al. · Proceedings of the National Academy of Sciences · 205
PDF
Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity
2020 · Lu Cui, Shih-Yu Chen, et al. · Nature Communications · 149
PDF
A human multi-lineage hepatic organoid model for liver fibrosis
2021 · Yuan Guan, Annika Enejder, et al. · Nature Communications · 148
PDF
Complex mammalian-like haematopoietic system found in a colonial chordate
2018 · Benyamin Rosental, Mark Kowarsky, et al. · Nature · 127
PDF
Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry
2018 · Veronica D. Gonzalez, Nikolay Samusik, et al. · Cell Reports · 116
PDF
High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
2021 · Veronica D. Gonzalez, Ying-Wen Huang, et al. · Cell Reports · 82
PDF
UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
2024 · Chuan He, Xixin Xing, et al. · Molecular Cell · 74
Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging
2021 · Xavier Rovira-Clavé, Sizun Jiang, et al. · Nature Communications · 74
PDF
Disrupted-in-Schizophrenia 1–mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling
2011 · Shih-Yu Chen, Pei-Hsin Huang, et al. · Proceedings of the National Academy of Sciences · 72
Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension
2017 · Toshie Saito, Kazuya Miyagawa, et al. · Circulation · 62
PDF
Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy
2015 · Nitya Nair, Henrik E Mei, et al. · Arthritis Research & Therapy · 59
Atomic mass tag of bismuth‐209 for increasing the immunoassay multiplexing capacity of mass cytometry
2017 · Guojun Han, Shih‐Yu Chen, et al. · Cytometry Part A · 51
PDF
NK cell receptor and ligand composition influences the clearance of SARS-CoV-2
2021 · Wan-Chen Hsieh, En-Yu Lai, et al. · Journal of Clinical Investigation · 48
PDF
Innate immune cell activation causes lung fibrosis in a humanized model of long COVID
2023 · Lu Cui, Zhuoqing Fang, et al. · Proceedings of the National Academy of Sciences · 43
Galectin-3 aggravates microglial activation and tau transmission in tauopathy
2023 · Jian Jing Siew, Hui-Mei Chen, et al. · Journal of Clinical Investigation · 41
PDF
Targeting pathogenic macrophages by the application of SHP-1 agonists reduces inflammation and alleviates pulmonary fibrosis
2023 · Shiao-Ya Hong, Ya-Ting Lu, et al. · Cell Death and Disease · 41
PDF
Epigenetic modulation of immune synaptic-cytoskeletal networks potentiates γδ T cell-mediated cytotoxicity in lung cancer
2021 · Rueyhung R. Weng, Hsuan-Hsuan Lu, et al. · Nature Communications · 41
PDF
Functions of axon guidance molecules in synapse formation
2009 · Shih-Yu Chen, Hwai-Jong Cheng · Current Opinion in Neurobiology · 39
PPARβ/δ-orchestrated metabolic reprogramming supports the formation and maintenance of memory CD8 + T cells
2024 · Alessio Bevilacqua, Fabien Franco, et al. · Science Immunology · 34
In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells
2017 · Sayak Mukherjee, Helle Jensen, et al. · Science Signaling · 29
Targeting the TRIM21-PD-1 axis potentiates immune checkpoint blockade and CAR-T cell therapy
2025 · Jie Shi, Zijian Zhang, et al. · Molecular Therapy · 26
NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration
2017 · Kasper Vadstrup, Elisabeth Douglas Galsgaard, et al. · Experimental and Molecular Pathology · 25
Works count: 86
Citation count: 2,545
H-index: 25
I10-index: 34
Year
Topic
Type