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Charles Le
Institution:
Theriva Biologics (United States)
Observed institution:
Theriva Biologics (United States)
ORCID:
0009-0007-5110-1185
Observed ORCID:
0009-0007-5110-1185
OpenAlex ID:
A5148899805
SYN-004 (ribaxamase) prevents New Onset Clostridium difficile Infection by Protecting the Integrity Gut Microbiome in a Phase 2b Study
2017
·
John Kokai-Kun
, Tracey Roberts
, et al.
·
Open Forum Infectious Diseases
·
8
Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
·
Clinical Cancer Research
·
4
1337. SYN-004 (Ribaxamase) Protects the Gut Microbiome of Patients Treated With Ceftriaxone From Disruption and Reduces the Emergence of Antimicrobial Resistance
2018
·
John Kokai-Kun
, Charles Le
, et al.
·
Open Forum Infectious Diseases
·
2
SYN-004 (Ribaxamase) Protects the Diversity of the Gut Microbiome in Patients Receiving Intravenous Ceftriaxone Treatment
2017
·
John Kokai-Kun
, Sheila Connelly
, et al.
·
Open Forum Infectious Diseases
·
2
Intravenous hyaluronidase-expressing oncolytic adenovirus with chemotherapy in metastatic pancreatic cancer: a randomized phase 2b trial
2026
·
Rocio Garcia-Carbonero
, Roberto Pazo Cid
, et al.
·
Nature Medicine
Table S5 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S6 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S3 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S11 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S6 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S10 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S7 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S4 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S8 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S9 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S9 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S1 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S1 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S4 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Supplementary Text 1 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S2 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S2 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Figure S5 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Table S3 from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
Data from Phase I Trial of Intravenous VCN-01 Oncolytic Adenovirus and Durvalumab in Patients with Head and Neck Metastatic Squamous Cell Carcinoma Refractory to Immunotherapy
2026
·
Maria Jove
, Irene Braña
, et al.
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29
Citation count:
16
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2
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