Concept

STAT6

OpenAlex ID: C145430368

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

1994 · Zhong Zhong, Zilong Wen, et al. · Science · 2,085

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

1996 · Mark H Kaplan, Ulrike Schindler, et al. · Immunity · 1,617

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The JAK-STAT Pathway at Twenty

2012 · George R. Stark, James E. Darnell · Immunity · 1,577

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Essential role of Stat6 in IL-4 signalling

1996 · Kiyoshi Takeda, Takashi Tanaka, et al. · Nature · 1,558

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1996 · Kazuya Shimoda, Jan van Deursent, et al. · Nature · 1,264

Signaling through the JAK/STAT pathway, recent advances and future challenges

2002 · T Kisseleva, S Bhattacharya, et al. · Gene · 1,167

Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

2018 · Shanshan Hu, Cameron Marshall, et al. · Frontiers in Immunology · 982

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

2002 · Douglas A. Kuperman, Xiaozhu Huang, et al. · Nature Medicine · 958

Control of Inflammation, Cytokine Expression, and Germinal Center Formation by BCL-6

1997 · Alexander L. Dent, Arthur L. Shaffer, et al. · Science · 950

Stat proteins and oncogenesis

2002 · Jacqueline Bromberg · Journal of Clinical Investigation · 863

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 · Jinzhao Hou, Ulrike Schindler, et al. · Science · 849

Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics

2013 · Leona A Doyle, Marina Vivero, et al. · Modern Pathology · 817

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Inhibition of Stat1-mediated gene activation by PIAS1

1998 · Bin Liu, Jiayu Liao, et al. · Proceedings of the National Academy of Sciences · 783

JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression

2019 · Katie L. Owen, Natasha K. Brockwell, et al. · Cancers · 728

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NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

2000 · Masaki Terabe, So Matsui, et al. · Nature Immunology · 708

Stat6-Independent GATA-3 Autoactivation Directs IL-4-Independent Th2 Development and Commitment

2000 · Wenjun Ouyang, Max Löhning, et al. · Immunity · 708

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Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

2006 · Zhi Chen, Arian Laurence, et al. · Proceedings of the National Academy of Sciences · 663

REGULATION OF TH2 DIFFERENTIATION AND Il4 LOCUS ACCESSIBILITY

2006 · K. Mark Ansel, Ivana Djuretic, et al. · Annual Review of Immunology · 652

Interleukin 25 promotes the initiation of proallergic type 2 responses

2007 · Pornpimon Angkasekwinai, Heon Park, et al. · The Journal of Experimental Medicine · 558

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Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

2012 · Pasquale Sansone, Jacqueline Bromberg · Journal of Clinical Oncology · 518

Interleukin‐4‐ and interleukin‐13‐mediated host protection against intestinal nematode parasites

2004 · Fred D. Finkelman, Terez Shea‐Donohue, et al. · Immunological Reviews · 518

Epigenetic regulation of the alternatively activated macrophage phenotype

2009 · Makoto Ishii, Haitao Wen, et al. · Blood · 505

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Early Transcription and Silencing of Cytokine Genes Underlie Polarization of T Helper Cell Subsets

2001 · Jane L. Grogan, Markus Mohrs, et al. · Immunity · 485

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Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease

2005 · Pratima Sinha, Virginia K Clements, et al. · The Journal of Immunology · 474

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Regulation of gene-activation pathways by PIAS proteins in the immune system

2005 · Ke Shuai, Bin Liu · Nature reviews. Immunology · 467

Works count: 2,088

Citation count: 105,100