Concept

IRF7

OpenAlex ID: C2776966659

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

2005 · Taro Kawai, Ken Takahashi, et al. · Nature Immunology · 2,599

IRF-7 is the master regulator of type-I interferon-dependent immune responses

2005 · Kenya Honda, Hideyuki Yanai, et al. · Nature · 2,289

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

2015 · David Roulois, Helen Loo Yau, et al. · Cell · 1,553

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Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

2004 · Taro Kawai, Shintaro Sato, et al. · Nature Immunology · 1,058

Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune Response

2006 · Daniel B. Stetson, Ruslan Medzhitov · Immunity · 1,034

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A Mouse Model of Zika Virus Pathogenesis

2016 · Helen M. Lazear, Jennifer Govero, et al. · Cell Host & Microbe · 913

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Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

2008 · Babacar Cisse, Michele L. Caton, et al. · Cell · 720

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How Toll-like receptors signal: what we know and what we don’t know

2005 · Luke AJ O’Neill · Current Opinion in Immunology · 614

IRF7: activation, regulation, modification and function

2011 · S Ning, J S Pagano, et al. · Genes and Immunity · 611

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Transcriptional Profiling of Interferon Regulatory Factor 3 Target Genes: Direct Involvement in the Regulation of Interferon-Stimulated Genes

2002 · Nathalie Grandvaux, Marc J. Servant, et al. · Journal of Virology · 525

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

2012 · Bradley N Bidwell, Clare Y Slaney, et al. · Nature Medicine · 507

Antiviral innate immunity pathways

2006 · Rashu B Seth, Lijun Sun, et al. · Cell Research · 501

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

2005 · Satoshi Uematsu, Shintaro Sato, et al. · The Journal of Experimental Medicine · 500

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

2015 · Michael J. Ciancanelli, Sarah X. L. Huang, et al. · Science · 489

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

2008 · Anna Yarilina, Kyung-Hyun Park-Min, et al. · Nature Immunology · 437

The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling

2005 · Annett Schoenemeyer, Betsy J. Barnes, et al. · Journal of Biological Chemistry · 417

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

2008 · Weiping Cao, Santhakumar Manicassamy, et al. · Nature Immunology · 416

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Loss of DExD/H Box RNA Helicase LGP2 Manifests Disparate Antiviral Responses

2007 · Thiagarajan Venkataraman, Maikel Valdes, et al. · The Journal of Immunology · 412

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Regulating IRFs in IFN Driven Disease

2019 · Caroline A. Jefferies · Frontiers in Immunology · 378

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Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells

2006 · Mari L Shinohara, Linrong Lu, et al. · Nature Immunology · 370

Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)

2006 · Christopher R Ingraham, Akira Kinoshita, et al. · Nature Genetics · 364

Activation with CpG-A and CpG-B Oligonucleotides Reveals Two Distinct Regulatory Pathways of Type I IFN Synthesis in Human Plasmacytoid Dendritic Cells

2003 · Miren Kerkmann, Simon Rothenfusser, et al. · The Journal of Immunology · 363

The tumour suppressor CYLD is a negative regulator of RIG‐I‐mediated antiviral response

2008 · Constantin S Friedman, Marie Anne O'Donnell, et al. · EMBO Reports · 338

The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways

2007 · Tiejun Zhao, Long Yang, et al. · Nature Immunology · 322

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

2013 · Peter Liehl, Vanessa Zuzarte-Luís, et al. · Nature Medicine · 319

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Works count: 1,740

Citation count: 60,140