Gene deletion
Concept
Analysis of optimality in natural and perturbed metabolic networks
2002 · Daniel Segrè, Dennis Vitkup, et al. · Proceedings of the National Academy of Sciences
Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast
2004 · Balázs Papp, Csaba Pál, et al. · Nature
Knockout mice created by TALEN-mediated gene targeting
2013 · Young Hoon Sung, In‐Jeoung Baek, et al. · Nature Biotechnology