Concept

Total synthesis

OpenAlex ID: C35753019

Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery

2000 · Stuart L. Schreiber · Science · 2,591

Cascade Reactions in Total Synthesis

2006 · K. C. Nicolaou, David J. Edmonds, et al. · Angewandte Chemie International Edition · 2,125

Olefin Metathesis and Beyond

2000 · Alois Fürstner · Angewandte Chemie International Edition · 1,975

The Diels-Alder Reaction in Total Synthesis

2002 · K. C. Nicolaou, Scott A. Snyder, et al. · Angewandte Chemie International Edition · 1,883

Organocatalytic cascade reactions as a new tool in total synthesis

2010 · Christoph Grondal, Matthieu Jeanty, et al. · Nature Chemistry · 1,597

A Planning Strategy for Diversity‐Oriented Synthesis

2003 · Martin D. Burke, Stuart L. Schreiber · Angewandte Chemie International Edition · 1,506

Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids

2003 · Christiane Marti, Erick M. Carreira · European Journal of Organic Chemistry · 1,468

C–H functionalization logic in total synthesis

2011 · Will R. Gutekunst, Phil S. Baran · Chemical Society Reviews · 1,410

Dearomatization Strategies in the Synthesis of Complex Natural Products

2011 · Stéphane P. Roche, John A. Porco · Angewandte Chemie International Edition · 1,350

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C‐3 Position

2010 · Feng Zhou, Yun‐Lin Liu, et al. · Advanced Synthesis & Catalysis · 1,257

Metathesis Reactions in Total Synthesis

2005 · K. C. Nicolaou, Paul G. Bulger, et al. · Angewandte Chemie International Edition · 1,196

A robotic platform for flow synthesis of organic compounds informed by AI planning

2019 · Connor W. Coley, Dale A. Thomas, et al. · Science · 1,137

Total synthesis of taxol

1994 · K. C. Nicolaou, Z. Yang, et al. · Nature · 1,122

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

2009 · Barry Trost, Megan Brennan · Synthesis · 1,083

Recent Developments in the Isonitrile‐Based Multicomponent Synthesis of Heterocycles

2003 · Jieping Zhu · European Journal of Organic Chemistry · 963

Gold catalysis in total synthesis

2008 · A. Stephen K. Hashmi, Matthias Rudolph · Chemical Society Reviews · 962

Control of four stereocentres in a triple cascade organocatalytic reaction

2006 · Dieter Enders, Matthias R. M. Hüttl, et al. · Nature · 911

Comprehensive organic functional group transformations II

2005 · Choice Reviews Online · 806

Prediction of Organic Reaction Outcomes Using Machine Learning

2017 · Connor W. Coley, Regina Barzilay, et al. · ACS Central Science · 774

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The art of total synthesis through cascade reactions

2009 · K. C. Nicolaou, Jason S. Chen · Chemical Society Reviews · 758

Construction of sulfur-containing moieties in the total synthesis of natural products

2019 · Nengzhong Wang, Puli Saidhareddy, et al. · Natural Product Reports · 756

Gold catalysis in total synthesis – recent achievements

2015 · Daniel Pflästerer, A. Stephen K. Hashmi · Chemical Society Reviews · 756

Collective synthesis of natural products by means of organocascade catalysis

2011 · Spencer B. Jones, Bryon Simmons, et al. · Nature · 737

RECAPRetrosynthetic Combinatorial Analysis Procedure: A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry

1998 · Xiao Qing Lewell, Duncan B. Judd, et al. · Journal of Chemical Information and Computer Sciences · 714

Cyclopropanation Strategies in Recent Total Syntheses

2017 · Christian Ebner, Erick M. Carreira · Chemical Reviews · 698

Works count: 32,860

Citation count: 727,400