Aryl hydrocarbon receptor nuclear translocator
Concept
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 · G L Wang, Bing‐Hua Jiang, et al. · Proceedings of the National Academy of Sciences
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 · Panu Jaakkola, David R. Mole, et al. · Science
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 · Patrick H. Maxwell, Michael S. Wiesener, et al. · Nature