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Pyruvate dehydrogenase complex
OpenAlex ID:
C88099638
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
2006
·
Jung-whan Kim
, Irina Tchernyshyov
, et al.
·
Cell Metabolism
·
3,891
PDF
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008
·
Heather R. Christofk
, Matthew G. Vander Heiden
, et al.
·
Nature
·
2,806
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
2006
·
Ioanna Papandreou
, Rob A. Cairns
, et al.
·
Cell Metabolism
·
2,255
PDF
Biology of Giardia lamblia
2001
·
Rodney D. Adam
·
Clinical Microbiology Reviews
·
1,225
Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate
1993
·
M Rohmer
, M Knani
, et al.
·
Biochemical Journal
·
1,200
PDF
SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways
2013
·
Jeongsoon Park
, Yue Chen
, et al.
·
Molecular Cell
·
986
PDF
Regulation of pyruvate metabolism and human disease
2013
·
Lawrence R. Gray
, Sean C. Tompkins
, et al.
·
Cellular and Molecular Life Sciences
·
951
PDF
Multinuclear NMR Studies on the Energy Metabolism of Glial and Neuronal Cells
1994
·
A. Brand
, C. Richter-Landsberg
, et al.
·
Developmental Neuroscience
·
879
Regulation of mitochondrial dehydrogenases by calcium ions
2009
·
Richard M. Denton
·
Biochimica et Biophysica Acta (BBA) - Bioenergetics
·
874
PDF
A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila , and Humans
2012
·
Daniel K. Bricker
, Eric B. Taylor
, et al.
·
Science
·
835
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
2012
·
Dimitrios Anastasiou
, Yimin Yu
, et al.
·
Nature Chemical Biology
·
817
Pyruvate Metabolism inSaccharomyces cerevisiae
1996
·
JACK T. PRONK
, H. YDE STEENSMA
, et al.
·
Yeast
·
784
PDF
Identification and Functional Expression of the Mitochondrial Pyruvate Carrier
2012
·
Sébastien Herzig
, Etienne Raemy
, et al.
·
Science
·
742
Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
2010
·
Sybille Mazurek
·
The International Journal of Biochemistry & Cell Biology
·
696
Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species
2004
·
Anatoly A. Starkov
, Gary Fiskum
, et al.
·
Journal of Neuroscience
·
692
PDF
Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
2014
·
Chendong Yang
, Bookyung Ko
, et al.
·
Molecular Cell
·
680
PDF
The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation
2014
·
Mulchand S. Patel
, Natalia S. Nemeria
, et al.
·
Journal of Biological Chemistry
·
672
PDF
α-KETO ACID DEHYDROGENASE COMPLEXES, X. REGULATION OF THE ACTIVITY OF THE PYRUVATE DEHYDROGENASE COMPLEX FROM BEEF KIDNEY MITOCHONDRIA BY PHOSPHORYLATION AND DEPHOSPHORYLATION
1969
·
Tracy C. Linn
, Flora H. Pettit
, et al.
·
Proceedings of the National Academy of Sciences
·
668
Relationships of Pyruvate and Lactate During Anaerobic Metabolism. I. Effects of Infusion of Pyruvate or Glucose and of Hyperventilation1
1958
·
William E. Huckabee
·
Journal of Clinical Investigation
·
664
PDF
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
2007
·
Jung-whan Kim
, Ping Gao
, et al.
·
Molecular and Cellular Biology
·
657
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
2008
·
E D Michelakis
, L Webster
, et al.
·
British Journal of Cancer
·
655
PDF
A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
2014
·
Gopinath Sutendra
, Adam Kinnaird
, et al.
·
Cell
·
633
PDF
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
2013
·
Joanna Kaplon
, Liang Zheng
, et al.
·
Nature
·
626
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
2005
·
Parvesh Bubber
, Vahram Haroutunian
, et al.
·
Annals of Neurology
·
622
UV-Assay with Pyruvate and NADH
1974
·
Hans Ulrich Bergmeyer
, Erich Bernt
·
Elsevier eBooks
·
617
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10,640
Citation count:
316,800
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