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Break Through Cancer

Alternate name: BTC
Country: US
ROR: 00a8me616
Crossref ID: 100020487
DOI: 10.13039/100020487
OpenAlex ID: F4320316669
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
2023 · Yanshuo Chu, Enyu Dai, et al. · Nature Medicine · 532
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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer
2024 · Julien Dilly, Megan T. Hoffman, et al. · Cancer Discovery · 328
Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics
2025 · Yunhe Liu, Ansam Sinjab, et al. · Cancer Cell · 305
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KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
2023 · Krishnan K. Mahadevan, Kathleen M. McAndrews, et al. · Cancer Cell · 286
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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer
2024 · Urszula N. Wasko, Jingjing Jiang, et al. · Nature · 236
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma
2024 · Daniel H. Shu, Won Jin Ho, et al. · Nature Immunology · 177
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Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications
2025 · Yunhe Liu, Yibo Dai, et al. · Cancer Cell · 175
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence
2023 · Shuming Zhang, Long Yuan, et al. · Genome Medicine · 164
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Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma
2024 · Marc Wehrli, Samantha Guinn, et al. · Clinical Cancer Research · 138
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Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival
2025 · Anna M. Varghese, Maria A. Perry, et al. · Nature Medicine · 136
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Resolving tissue complexity by multimodal spatial omics modeling with MISO
2025 · Kyle Coleman, Amelia Schroeder, et al. · Nature Methods · 106
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Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker
2023 · Martin S. Taylor, Connie Wu, et al. · Cancer Discovery · 102
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A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer
2024 · Anupriya Singhal, Hannah C. Styers, et al. · Cancer Discovery · 96
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Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories
2025 · Jeanette A.I. Johnson, Daniel R. Bergman, et al. · Cell · 83
Response and Resistance to RAS Inhibition in Cancer
2025 · Richard Y. Ebright, Julien Dilly, et al. · Cancer Discovery · 81
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PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration
2024 · Alexander T.F. Bell, Jacob T. Mitchell, et al. · Cell Systems · 78
Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review
2023 · Ryan M. Kahn, Sushmita Gordhandas, et al. · JAMA Surgery · 78
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Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths
2023 · Mariela Cortés-López, Paulina Chamely, et al. · Cell stem cell · 70
Human Pancreatic Cancer Single-Cell Atlas Reveals Association of CXCL10+ Fibroblasts and Basal Subtype Tumor Cells
2024 · Ian M. Loveless, Samantha B. Kemp, et al. · Clinical Cancer Research · 67
Multiplex Digital Methylation‐Specific PCR for Noninvasive Screening of Lung Cancer
2023 · Yang Zhao, Christine M. O'Keefe, et al. · Advanced Science · 67
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Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial
2024 · Evanthia.T. Roussos Torres, Won J. Ho, et al. · Nature Cancer · 62
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Messenger RNA vaccines for cancer immunotherapy: progress promotes promise
2022 · Amanda L. Huff, Elizabeth M. Jaffee, et al. · Journal of Clinical Investigation · 62
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Correcting the drug development paradigm for glioblastoma requires serial tissue sampling
2023 · Kirit Singh, Kelly M. Hotchkiss, et al. · Nature Medicine · 60
Alliance A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer
2024 · Janet A. Alvarez, Qian Shi, et al. · BMC Cancer · 57
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Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients
2023 · Alex S. Genshaft, Sonu Subudhi, et al. · Hepatology · 57
Works count: 211
Citation count: 5,418
H-index: 35
I10-index: 95
2-year mean citedness: 20.87
Awards count: 3
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