Regulation of the mTOR Pathway by Nutrients
Description: Growth is the fundamental process through which cells and organisms accumulate mass and increase in size. In mammals we are studying the major regulator of growth, a network of signaling proteins called the mTOR Complex 1 (mTORC1) pathway. Our overall goals are to understand how nutrients, such as amino acids and glucose, communicate to mTORC1 through the GATOR2 complex and the role of this communication in vivo.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R01
Start date: 2004-03-23
End date: 2024-03-31
Investigator: JONATHAN S. WEISSMAN
Institution: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 187
Funder award ID: R01CA103866
OpenAlex ID: G4673634134