Award

Intestinal Stem Cell Culture and Entero-Endocrine Lineage Development

Description: PUBLIC HEALTH RELEVANCE: Our understanding of intestinal stem cell biology has increased dramatically over the last five years. The goal of this grant application is to use human intestinal samples to understand how intestinal stem cells are influenced by stress condition that alters how they divide and mature, and the role of other cells in the intestine that controls these changes. We believe that at the completion of this study, we will be able to define the mediators that control these stem cell characteristics, which will lead to novel cellular therapies.

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Funding type: cooperative_agreement

Funder scheme: U01

Start date: 2009-09-30

End date: 2020-08-31

Investigator: JAMES C DUNN

Institution: UNIVERSITY OF CALIFORNIA LOS ANGELES

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Funded outputs count: 40

Funder award ID: U01DK085535

OpenAlex ID: G3756884340