Epidemiology of Biomarkers of AMD Progression
Description: Project Narrative Despite effective treatments for choroidal neovascularization, age-related macular degeneration (AMD) remains the leading cause of blindness in the US due to the eventual development of atrophy in the long-term. As current attempts to develop therapies to slow the progression of atrophy have met with limited success, earlier intervention would be desirable, and could be possible if endpoints and biomarkers to assess progression early in the disease were available. By studying the epidemiology of AMD progression over 7 years, the proposed research will identify these critical biomarkers and develop a staging system for AMD which is essential to enable early intervention clinical trials for AMD.
Funder: National Eye Institute
Funding type: research
Funder scheme: R01
Start date: 2021-09-30
End date: 2027-08-31
Investigator: JONATHAN L HAINES
Institution: DOHENY EYE INSTITUTE
Funded outputs count: 20
Funder award ID: R01EY030614
OpenAlex ID: G9000903909