Platelet Derived Growth Factor Mediated Activation and Rejuvenation of Endogenous Cardiac Stem Cells
Description: The burden of heart failure is underpinned by the heart’s limited capacity for self-repair after injury. Recent evidence shows that PDGF can improve heart function by activating and rejuvenating resident heart stem cells. This project will build on over a decade of preliminary work in mice, validating our results in a preclinical large animal model. Outcomes of this project include expedited progression of this promising therapy where thousands of heart failure patients could one-day benefit.
Amount: A$102,300
Funding type: fellowship
Funder scheme: Postgraduate Scholarships - Medical/Dental Postgraduate Scholarship
Start date: 2016-01-01
End date: 2018-12-31
Investigator: Sujitha Thavapalachandran
Institution: University of Sydney
Funded outputs count: 3
Funder award ID: 1114472
OpenAlex ID: G107567460