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Leveraging routinely collected and linked research data to study the causes and consequences of common mental disorders

Description: Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Funding type: intramural
Start date: 2018-03-30
End date: 2020-12-31
Funded outputs count: 135
Funder award ID: MC_PC_17209
OpenAlex ID: G6501369756
Depression detectives: piloting a methodology for online co-produced research
2026 · Sophia Collins, Christine Kupfer, et al. · Research Involvement and Engagement
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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
2026 · Nora I. Strom, Brad Verhulst, et al. · Nature Genetics · 31
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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
2024 · Nora I. Strom, Brad Verhulst, et al. · medRxiv · 27
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The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses
2024 · Rosie M. Walker, Michael Chong, et al. · Translational Psychiatry · 14
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Uncovering the Genetic Architecture of Major Depression
2024 · Sullivan P.F, Lewis C.M, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo
2024 · Cynthia H. Y. Fu, Mathilde Antoniades, et al. · Nature Mental Health · 39
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Disrupted limbic-prefrontal effective connectivity in response to fearful faces in lifetime depression
2024 · Aleks Stolicyn, Mathew A. Harris, et al. · Journal of Affective Disorders · 8
Violations of physical and psychological expectations in the human adult brain
2024 · Shari Liu, Kirsten Lydic, et al. · Imaging Neuroscience · 22
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Childhood cognitive ability and self-harm and suicide in later life
2023 · Matthew H. Iveson, Emily L. Ball, et al. · SSM - Population Health · 2
Classification accuracy of structural and functional connectomes across different depressive phenotypes
2023 · Hon Wah Yeung, Aleks Stolicyn, et al. · Imaging Neuroscience · 2
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Childhood intelligence and risk of depression in later-life: A longitudinal data-linkage study
2023 · Emily L. Ball, Drew M. Altschul, et al. · SSM - Population Health · 2
Views on sharing mental health data for research purposes: qualitative analysis of interviews with people with mental illness
2023 · Emily Watson, Sue Fletcher-Watson, et al. · BMC Medical Ethics · 18
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The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses
2023 · Rosie May Walker, Michael Chong, et al. · medRxiv · 1
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Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals
2023 · Robert F. Hillary, Daniel L. McCartney, et al. · PLoS Medicine · 69
Pathway-Based Polygenic Risk Scores for Schizophrenia and Associations With Reported Psychotic-like Experiences and Neuroimaging Phenotypes in the UK Biobank
2023 · Miruna C. Barbu, Maria Viejo-Romero, et al. · Biological Psychiatry Global Open Science · 6
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
2023 · Cynthia H. Y. Fu, Guray Erus, et al. · BMC Psychiatry · 20
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Predicting sex, age, general cognition and mental health with machine learning on brain structural connectomes
2022 · Hon Wah Yeung, Aleks Stolicyn, et al. · Human Brain Mapping · 30
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Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
2022 · Jonathan Higham, Lyndsay Kerr, et al. · Genome biology · 32
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Patient satisfaction with mental and physical health services: Findings from a UK-wide online survey
2022 · Elizabeth J. Kirkham, Sue Fletcher-Watson, et al. · Wellcome Open Research · 8
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Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK Biobank
2022 · Miruna C. Barbu, Gladi Thng, et al. · medRxiv · 1
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AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
2022 · Cynthia H. Y. Fu, Guray Erus, et al. · Research Square · 1
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Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis
2022 · Andrew D. Grotzinger, Travis T. Mallard, et al. · Nature Genetics · 333
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Effects of depression on employment and social outcomes: a Mendelian randomisation study
2022 · Desmond Campbell, Michael James Green, et al. · Journal of Epidemiology & Community Health · 51
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Virtual Ontogeny of Cortical Growth Preceding Mental Illness
2022 · Yash Patel, Jean Shin, et al. · Biological Psychiatry · 35
Experience of clinical services shapes attitudes to mental health data sharing: findings from a UK-wide survey
2022 · E.J. Kirkham, S. M. Lawrie, et al. · BMC Public Health · 15
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