Lymphatic drainage dysfunction in chronic hypertension
Description: Project Narrative Malfunction of the brain’s waste clearing glymphatic system has been shown to play a key role in cerebral small vessel disease (cSVD) the most common cause of cognitive impairment with chronic hypertension. Remarkably, the status of the lymphatic system (LS) has not been investigated in cSVD. We have novel data showing functional impairment of the LS in chronic hypertension and here we explore the novel idea that these pathological alterations contributes to cSVD.
Funder: National Institutes of Health
Amount: $773,000
Funding type: research
Funder scheme: R01
Start date: 2024-07-15
End date: 2028-05-31
Investigator: HELENE D BENVENISTE
Institution: YALE UNIVERSITY
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Funded outputs count: 1
Funder award ID: 1r01hl176017-01
OpenAlex ID: G1186659969