The Role of Glutathione Reductase in Age-related Hearing Loss
Description: Age-related hearing loss (AHL) is a common feature of mammalian aging and is the most frequently occurring sensory disorder in the elderly population. The main goal of this proposed project is to determine the role and the molecular mechanisms of the antioxidant enzyme glutathione reductase in AHL. Knowledge of these molecular mechanisms has enormous potential for improving health outcomes through the discovery/development of novel therapeutics for human AHL and other age-related sensory disorders.
Funding type: research
Funder scheme: R03
Start date: 2011-07-01
End date: 2015-06-30
Investigator: SHINICHI SOMEYA
Institution: UNIVERSITY OF FLORIDA
Funded outputs count: 37
Funder award ID: R03DC011840
OpenAlex ID: G4471501823