Evaluation of Molecular Mechanisms of Treatment Response in Late Life Depression
Description: Using advanced molecular approaches, we will determine the biological mechanisms related to treatment response in late-life depression. Our proposed study will also develop a predictive tool combining neurocognitive, neuroimaging, and protein data to identify who with late-life depression is more likely to have no benefit from antidepressant treatment at the outset of therapy. The goal of the study is to clarify the mechanisms of treatment response in late-life depression, and whether we can effectively identify those who will benefit from antidepressant therapy at the outset of treatment.
Funding type: research
Funder scheme: R01
Start date: 2019-07-01
End date: 2024-03-31
Investigator: BRENO SATLER DINIZ
Institution: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
Funded outputs count: 13
Funder award ID: R01MH118311
OpenAlex ID: G4406260869