Award

Mayo Alzheimer's Disease Research Center

Description: NARRATIVE – OVERALL The Mayo Clinic Alzheimer's Disease Research Center (ADRC) will pursue the theme of Multiple Etiology Dementias. The ADRC will intensely focus its efforts on the recruitment on African American/Black, Hispanic/Latino, and rural dwelling communities, and will assess for all ADRC participants' structural and social determinants of health to evaluate the impact of multiple pathologies. Mayo ADRC will share its data, images, and biological specimens widely with the ADRC community and other investigators.

Funder: National Institute on Aging

Funding type: program

Funder scheme: P30

Start date: 2019-07-01

End date: 2029-04-30

Investigator: BRADLEY F BOEVE

Institution: MAYO CLINIC ROCHESTER

Funded outputs count: 948

Funder award ID: P30AG062677

OpenAlex ID: G9000899208

Feature harmonization reveals that apparent cross-cohort differences in tau-positivity prediction reflect variable availability and cohort stage structure

2026 · Avinay Bhat, Mattia Cestari, et al. · medRxiv

Charting Cervical Spinal Cord Morphometry Across the Lifespan

2026 · Kurt G. Schilling, Michael E. Kim, et al. · Human Brain Mapping

Hemispheric Asymmetry of Neuroimaging Biomarkers in Early Onset Alzheimer's Disease: Clinical and Cognitive Outcomes

2026 · Jacob Ziontz, Ganna Blazhenets, et al. · Annals of Neurology

Vision Impairment, Vision Correction, and Dementia Risk in Mild Cognitive Impairment

2026 · Huilin Tang, David A. Wolk, et al. · Journal of the American Geriatrics Society

Incident versus prevalent progressive supranuclear palsy: analyses of U.S. Alzheimer’s Disease Research Centers data indicate clinical and neuropathological features of a relatively common and underrecognized tauopathy in the aging brain

2026 · Benjamin J. Cushing, Ryan K. Shahidehpour, et al. · Acta Neuropathologica

Generalizing Amyloid β Pathology from Postmortem Human Brains with Vision Foundation Models for Lesion Quantification

2026 · Yuheng Chen, Baayla D.C. Boon, et al. · medRxiv

Monospecific antibodies reveal reduction of granulins in frontotemporal dementia caused by GRN mutations

2026 · Paola Merino, Ludmilla Troiano Araujo, et al. · Molecular Neurodegeneration Advances

A model of brain function to predict tau across Alzheimer’s disease and related disorders

2026 · Nick Corriveau-Lecavalier, Gemeng Zhang, et al. · Nature Communications

Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers

2026 · Dror Shir, Alicia Algeciras-Schimnich, et al. · Neurology

Frontotemporal lobar degeneration therapeutic development pipeline: 2026

2026 · Alberto Benussi, Aurora Saccavini, et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions

Sphingolipid and ceramide associations with tau pathology vary across diverse ethnoracial groups in postmortem brain tissue

2026 · Annalise Schweickart, Richa Batra, et al. · Alzheimer s & Dementia

Attention‐deficit/hyperactivity disorder polygenic risk score and incidence of cognitive impairment in older adults: A prospective multicohort study

2026 · Douglas Teixeira Leffa, Guilherme Bauer‐Negrini, et al. · Alzheimer s & Dementia

Explainable AI framework for Alzheimer’s disease prediction using multimodal data

2026 · Aunsia Khan, Anusha Achuthan, et al. · Scientific Reports

Optimal cutoffs for the Montreal Cognitive Assessment among English and Spanish speaking Latinos

2026 · Jaime Perales-Puchalt, Andrew J. Aschenbrenner, et al. · Applied Neuropsychology Adult

Diagnostic accuracy of remote self-administered digital cognitive assessment by clinical diagnosis and Alzheimer’s disease PET imaging biomarkers

2026 · Nikki H. Stricker, Elizabeth A. Boots, et al. · medRxiv

Using machine learning of neuroimaging and mitochondrial haplogroups to predict maternal family history of Alzheimer’s disease

2026 · Olivia J. Veatch, Sreejata Dutta, et al. · PLOS Aging and Health

Targeted single-nucleus sequencing of 39,800 neurons reveals extensive low-frequency somatic variants

2026 · Vanshika Bidhan, Sarah Wynants, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Neurofibrillary tangle deposition in primary idiotypic isocortices using flortaucipir PET in histopathologically confirmed Alzheimer’s disease

2026 · Keith A. Josephs, Stephen D. Weigand, et al. · iScience

Charting confidence in white matter brain charts: enabling study planning through stability validation

2026 · Michael E. Kim, Gaurav Rudravaram, et al. · Journal of medical imaging

Integrative Analysis of Heterogeneous Multisource Partly Interval‐Censored Data

2026 · Li Jin, Tao Hu · Statistical Analysis and Data Mining The ASA Data Science Journal

Beyond motor symptoms: associations between sleep disorders and multidomain functional decline in Parkinson’s disease

2026 · Chao Tang, Jiaxin Yang, et al. · npj Parkinson s Disease

Feasibility of remote self-administered cognitive assessment in an Alzheimer’s disease treatment clinic

2026 · Alyssa N. Kaser, John L. Stricker, et al. · medRxiv

Cohabitation status influences subjective informant reports of daily functioning in aging Asian American adults

2026 · Jennifer Lozano, Claudine Lim Oliva, et al. · Applied Neuropsychology Adult

A Flexible-Horizon Clinical Decision Support Model for Dementia Early Detection and Risk Prediction in Secondary Care: A Responsible AI Approach

2026 · Adnane Ez-zizi, Kalyan Seelam, et al. · Journal of Medical Systems

Rare extreme polygenic risk scores strongly indicate Alzheimer’s disease risk

2026 · Elizabeth L. Ward, Peter T. Nelson, et al. · medRxiv