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R37DK047119

Funded outputs count: 60
Funder award ID: R37DK047119
OpenAlex ID: G1292063993
Negative feedback by IRE1β optimizes mucin production in goblet cells
2013 · Akio Tsuru, Naoko Fujimoto, et al. · Proceedings of the National Academy of Sciences · 165
Protein-Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation
2012 · D. Ron, H. P. Harding · Cold Spring Harbor Perspectives in Biology · 109
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The ER stress transducer IRE1β is required for airway epithelial mucin production
2012 · M B Martino, L Jones, et al. · Mucosal Immunology · 191
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Endoplasmic Reticulum Thiol Oxidase Deficiency Leads to Ascorbic Acid Depletion and Noncanonical Scurvy in Mice
2012 · Ester Zito, Henning Gram Hansen, et al. · Molecular Cell · 116
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ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load
2012 · Joseph E. Chambers, Kseniya Petrova, et al. · The Journal of Cell Biology · 89
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Increased Intestinal Lipid Absorption Caused by Ire1β Deficiency Contributes to Hyperlipidemia and Atherosclerosis in Apolipoprotein E–Deficient Mice
2012 · Jahangir Iqbal, Joyce Queiroz, et al. · Circulation Research · 27
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Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides
2011 · Ningguo Gao, Jie Shang, et al. · Molecular Biology of the Cell · 34
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation‐coupled calcium release and response to hemodynamic load
2011 · King‐Tung Chin, Guoxin Kang, et al. · The FASEB Journal · 56
Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin
2010 · Ester Zito, Eduardo Pinho Melo, et al. · Molecular Cell · 319
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Structural Determinants of PERK Inhibitor Potency and Selectivity
2010 · Hong Wang, Jaime Blais, et al. · Chemical Biology & Drug Design · 34
The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
2010 · Jiangbin Ye, Monika Kumanova, et al. · The EMBO Journal · 702
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A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity
2010 · Jaime D. Blais, King-Tung Chin, et al. · Journal of Biological Chemistry · 114
Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
2010 · R. Luke Wiseman, Yuhong Zhang, et al. · Molecular Cell · 190
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ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis
2010 · Ester Zito, King-Tung Chin, et al. · The Journal of Cell Biology · 247
Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR
2010 · Jiahui Tao, Kseniya Petrova, et al. · Journal of Molecular Biology · 25
The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans
2010 · Cole M. Haynes, Yun Yang, et al. · Molecular Cell · 497
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Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling
2009 · Connie W. Woo, Dongying Cui, et al. · Nature Cell Biology · 281
Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis
2009 · Gang Li, Marco Mongillo, et al. · The Journal of Cell Biology · 596
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Infectious tolerance via the consumption of essential amino acids and mTOR signaling
2009 · Stephen P. Cobbold, Elizabeth Adams, et al. · Proceedings of the National Academy of Sciences · 336
Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP
2009 · Edward Thorp, Gang Li, et al. · Cell Metabolism · 340
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Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
2009 · Heather P. Harding, Yuhong Zhang, et al. · Proceedings of the National Academy of Sciences · 266
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells
2009 · Qiuyan Wang, Helena Mora-Jensen, et al. · Proceedings of the National Academy of Sciences · 343
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Divergent Effects of PERK and IRE1 Signaling on Cell Viability
2009 · Jonathan H. Lin, Han Li, et al. · PLoS ONE · 305
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Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
2008 · Kseniya Petrova, Seiichi Oyadomari, et al. · The EMBO Journal · 139
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Enhanced Integrated Stress Response Promotes Myelinating Oligodendrocyte Survival in Response to Interferon-γ
2008 · Wensheng Lin, Phillip E. Kunkler, et al. · American Journal Of Pathology · 100
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