Get started
Award

Ubiquitin Function In Eye Lens

Funding type: research
Funder scheme: R01
Start date: 2001-04-01
End date: 2015-02-28
Investigator: ALLEN TAYLOR
Institution: TUFTS UNIVERSITY BOSTON
Funded outputs count: 74
Funder award ID: R01EY013250
OpenAlex ID: G5785578123
Mechanistic targeting of advanced glycation end-products in age-related diseases
2018 · Sheldon Rowan, Eloy Bejarano, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 215
Too sweet: Problems of protein glycation in the eye
2018 · Eloy Bejarano, Allen Taylor · Experimental Eye Research · 64
Stabilization of p27 Kip1 /CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell‐cycle control
2018 · Elizabeth A. Whitcomb, Yien Che Tsai, et al. · The FASEB Journal · 18
Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes
2018 · Chung‐Jung Chiu, Naila Rabbani, et al. · BioFactors · 38
Gut microbiota modify risk for dietary glycemia-induced age-related macular degeneration
2018 · Sheldon Rowan, Allen Taylor · Gut Microbes · 45
PDF
Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration
2017 · Sheldon Rowan, Shuhong Jiang, et al. · Proceedings of the National Academy of Sciences · 273
Visualization of Dietary Patterns and Their Associations With Age-Related Macular Degeneration
2017 · Chung-Jung Chiu, Min-Lee Chang, et al. · Investigative Ophthalmology & Visual Science · 33
PDF
Associations between Periodontal Microbiota and Death Rates
2016 · Chung-Jung Chiu, Min-Lee Chang, et al. · Scientific Reports · 9
PDF
Disassembly of the lens fiber cell nucleus to create a clear lens: The p27 descent
2016 · Sheldon Rowan, Min-Lee Chang, et al. · Experimental Eye Research · 35
Unfolded‐protein response‐associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract
2015 · Lei Lyu, Elizabeth A. Whitcomb, et al. · The FASEB Journal · 34
Dietary glycemia as a determinant of health and longevity
2015 · Elizabeth A. Whitcomb, Chung-Jung Chiu, et al. · Molecular Aspects of Medicine · 16
Dietary Glycemia Reversibly Contributes to Age‐related Macular Degeneration and Metabolic Disease in Aged C57Bl/6J Mice
2015 · Sheldon Rowan, Min‐Lee Chang, et al. · The FASEB Journal
Ubiquitination Catalyzed by the Ubiquitin Conjugating Enzyme, UbcH7 Inhibits the Degradation of Proteasome Substrates
2015 · Elizabeth Whitcomb, Allen Taylor · The FASEB Journal
Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract
2015 · Ke Liu, Lei Lyu, et al. · Proceedings of the National Academy of Sciences · 68
Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly
2014 · Blake R. Chaffee, Fu Shang, et al. · Development · 67
The Relationship of Major American Dietary Patterns to Age-Related Macular Degeneration
2014 · Chung-Jung Chiu, Min-Lee Chang, et al. · American Journal of Ophthalmology · 129
Newborn Mouse Lens Proteome and Its Alteration by Lysine 6 Mutant Ubiquitin
2014 · Fu Shang, Phillip A. Wilmarth, et al. · Journal of Proteome Research · 11
PDF
High Glucose Activates ChREBP-Mediated HIF-1α and VEGF Expression in Human RPE Cells Under Normoxia
2014 · Min-Lee Chang, Chung-Jung Chiu, et al. · Advances in experimental medicine and biology · 36
Cfh Genotype Interacts With Dietary Glycemic Index to Modulate Age-Related Macular Degeneration-Like Features in Mice
2013 · Sheldon Rowan, Karen Weikel, et al. · Investigative Ophthalmology & Visual Science · 20
PDF
Common Cell Biologic and Biochemical Changes in Aging and Age-Related Diseases of the Eye: Toward New Therapeutic Approaches to Age-Related Ocular Diseases
2013 · Elizabeth A. Whitcomb, Fu Shang, et al. · Investigative Ophthalmology & Visual Science · 6
Nutritional modulation of cataract
2013 · Karen A Weikel, Caren Garber, et al. · Nutrition Reviews · 125
Synchrotron infrared imaging of advanced glycation endproducts (AGEs) in cardiac tissue from mice fed high glycemic diets
2013 · Giovanni Birarda, Elizabeth A. Holman, et al. · Biomedical Spectroscopy and Imaging · 22
PDF
The Ubiquitin Conjugating Enzyme UbcH7, controls cell migration
2013 · Elizabeth A. Whitcomb, Aurelie Le Feuvre, et al. · The FASEB Journal
Enhancement of Ubiquitin Conjugation Activity Reduces Intracellular Aggregation of V76D Mutant γD-Crystallin
2012 · Zhenzhen Liu, Allen Taylor, et al. · Investigative Ophthalmology & Visual Science · 8
PDF
Mechanistically linking age-related diseases and dietary carbohydrate via autophagy and the ubiquitin proteolytic systems
2012 · Allen Taylor · Autophagy · 21
PDF
Year
Topic