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Center for Cell Circuits

Funding type: program
Funder scheme: P50
Start date: 2011-07-09
End date: 2016-04-30
Investigator: AVIV REGEV
Institution: BROAD INSTITUTE, INC.
Funded outputs count: 147
Funder award ID: P50HG006193
OpenAlex ID: G6109581923
High-throughput RNA isoform sequencing using programmed cDNA concatenation
2023 · Aziz M. Al’Khafaji, Jonathan T. Smith, et al. · Nature Biotechnology · 200
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A genome-wide optical pooled screen reveals regulators of cellular antiviral responses
2023 · Rebecca J. Carlson, Michael D. Leiken, et al. · Proceedings of the National Academy of Sciences · 39
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
2023 · Matteo Gentili, Bingxu Liu, et al. · Nature Communications · 145
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The phenotypic landscape of essential human genes
2022 · Luke Funk, Kuan-Chung Su, et al. · Cell · 169
ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling
2022 · Matteo Gentili, Bingxu Liu, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Hijacking of transcriptional condensates by endogenous retroviruses
2022 · Vahid Asimi, Abhishek Sampath Kumar, et al. · Nature Genetics · 80
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Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
2022 · Kousuke Mouri, Michael H. Guo, et al. · Nature Genetics · 71
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Pooled genetic perturbation screens with image-based phenotypes
2022 · David Feldman, Luke Funk, et al. · Nature Protocols · 59
Topological isolation of developmental regulators in mammalian genomes
2021 · Hua-Jun Wu, Alexandro Landshammer, et al. · Nature Communications · 29
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Genome-wide enhancer maps link risk variants to disease genes
2021 · Joseph Nasser, Drew T. Bergman, et al. · Nature · 669
Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis
2021 · Adriano Bolondi, Leah Haut, et al. · BIO-PROTOCOL · 8
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Emergence and Patterning Dynamics of Mouse Definitive Endoderm
2021 · Maayan Pour, Abhishek Sampath Kumar, et al. · iScience · 31
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Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
2020 · Jesse V. Veenvliet, Adriano Bolondi, et al. · Science · 333
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Loss of the Nuclear Protein RTF2 Enhances Influenza Virus Replication
2020 · Bing Shao Chia, Bo Li, et al. · Journal of Virology · 9
Epigenetic regulator function through mouse gastrulation
2020 · Stefanie Grosswendt, Helene Kretzmer, et al. · Nature · 143
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Unblending of Transcriptional Condensates in Human Repeat Expansion Disease
2020 · Shaon Basu, Sebastian D. Mackowiak, et al. · Cell · 198
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Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features
2020 · John P. Ray, Carl G. de Boer, et al. · Nature Communications · 76
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An immune-cell signature of bacterial sepsis
2020 · Miguel Reyes, Michael R. Filbin, et al. · Nature Medicine · 496
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Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
2020 · Bo Li, Sara M. Clohisey, et al. · Nature Communications · 238
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IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development
2019 · Amy Li, Rebecca H. Herbst, et al. · Cell Reports · 83
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Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses
2019 · Antonia Wallrapp, Patrick R. Burkett, et al. · Immunity · 263
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Optical Pooled Screens in Human Cells
2019 · David Feldman, Avtar Singh, et al. · Cell · 321
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Differential regulation of OCT4 targets facilitates reacquisition of pluripotency
2019 · Sudhir Thakurela, Camille Sindhu, et al. · Nature Communications · 2
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Transcriptomic Analysis and High-dimensional Phenotypic Mapping of Mononuclear Phagocytes in Mesenteric Lymph Nodes Reveal Differences Between Ulcerative Colitis and Crohn’s Disease
2019 · Laurence Chapuy, Marwa Bsat, et al. · Journal of Crohn s and Colitis · 18
Simultaneous Profiling of Gene Expression and Chromatin Accessibility in Single Cells
2019 · Miguel Reyes, Kianna Billman, et al. · Advanced Biosystems · 48
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