The Manhattan HIV Brain Bank
Description: NARRATIVE Nervous system disorders are common in people living with HIV/AIDS (PLWHA), despite the ability to control HIV replication with combined antiretroviral therapies. One barrier to understanding whether HIV establishes a reservoir in the nervous system, and what causes neurologic disease, is a paucity of well characterized brain tissues from PLWHA. The Manhattan HIV Brain Bank, member of the National NeuroAIDS Tissue Consortium, was created to provide just such a research resource. It conducts a longitudinal study of PLWHA who are willing to be organ donors for research upon demise, and has created a biorepository of well-characterized nervous system and systemic tissues to assist neuroAIDS and AIDS researchers in translational studies to help find better therapies for HIV and nervous system disorders.
Funding type: cooperative_agreement
Funder scheme: U24
Start date: 2013-05-01
End date: 2024-02-29
Investigator: SUSAN MORGELLO
Institution: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Funded outputs count: 232
Funder award ID: U24MH100931
OpenAlex ID: G4318681234