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I01 BX000933

Funded outputs count: 20
Funder award ID: I01 BX000933
OpenAlex ID: G1362799485
APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology
2024 · Augustine Chemparathy, Yann Le Guen, et al. · Neuron · 44
A familial missense variant in the Alzheimer’s disease gene SORL1 impairs its maturation and endosomal sorting
2024 · Elnaz Fazeli, Daniel D. Child, et al. · Acta Neuropathologica · 30
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Weight Loss Is a Strong Predictor of Memory Disorder Independent of Genetic Influences
2023 · Sunny Chen, Sara M. Sarasua, et al. · Genes · 2
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APOE Locus-Associated Mitochondrial Function and Its Implication in Alzheimer’s Disease and Aging
2023 · Eun-Gyung Lee, Lesley Leong, et al. · International Journal of Molecular Sciences · 16
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A Preliminary Comparison of the Methylome and Transcriptome from the Prefrontal Cortex Across Alzheimer’s Disease and Lewy Body Dementia
2023 · Daniel W. Fisher, Jessica Tulloch, et al. · Journal of Alzheimer s Disease Reports · 9
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TOMM40 genetic variants associated with healthy aging and longevity: a systematic review
2022 · Sunny Chen, Sara M. Sarasua, et al. · BMC Geriatrics · 33
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TOMM40 RNA Transcription in Alzheimer’s Disease Brain and Its Implication in Mitochondrial Dysfunction
2021 · Eun-Gyung Lee, Sunny Chen, et al. · Genes · 41
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Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry
2020 · Elizabeth E. Blue, Anqi Cheng, et al. · JAMA Network Open · 17
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Lack of APOE Christchurch variant in five age of onset outliers with PSEN1, PSEN2 Alzheimer's disease and MAPT frontotemporal dementia
2020 · Chang-En Yu, Sunny Chen, et al. · Journal of the Neurological Sciences · 3
Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease
2020 · Eun-Gyung Lee, Jessica Tulloch, et al. · PLoS ONE · 51
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Glia-specific APOE epigenetic changes in the Alzheimer’s disease brain
2018 · Jessica Tulloch, Lesley Leong, et al. · Brain Research · 57
APOE DNA methylation is altered in Lewy body dementia
2018 · Jessica Tulloch, Lesley Leong, et al. · Alzheimer s & Dementia · 31
DNA methylation of TOMM40-APOE-APOC2 in Alzheimer’s disease
2018 · Yvonne Shao, McKenzie Shaw, et al. · Journal of Human Genetics · 85
The APOE Gene is Differentially Methylated in Alzheimer’s Disease
2015 · Jessica Foraker, Steven P. Millard, et al. · Journal of Alzheimer s Disease · 143
Erratum to: Epigenetic considerations of the APOE gene
2015 · Chang-En Yu, Jessica Foraker · BioMolecular Concepts · 3
Epigenetic considerations of the APOE gene
2015 · Chang-En Yu, Jessica Foraker · BioMolecular Concepts · 21
Epigenetic signature and enhancer activity of the human APOE gene
2013 · Chang-En Yu, Eiron Cudaback, et al. · Human Molecular Genetics · 72
MicroRNA in Alzheimer’s disease: an exploratory study in brain, cerebrospinal fluid and plasma
2013 · Lynn M. Bekris, Franziska Lutz, et al. · Biomarkers · 117
TOMM40 intron 6 poly‐T length, age at onset, and neuropathology of AD in individuals with APOE ɛ3/ɛ3
2012 · Ge Li, Lynn M. Bekris, et al. · Alzheimer s & Dementia · 31
Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE
2011 · Lynn M Bekris, Franziska Lutz, et al. · Journal of Human Genetics · 99
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