Cellular Mechanisms of Auditory Information Processing
Description: PUBLIC HEALTH RELEVANCE: The neural mechanisms of sensory processing in the brain underlie our normal perceptual abilities, which in hearing include the detection and identification of sound sources and the ability to communicate through sound. The central neural mechanisms change in response to damage to the sensory organs. Consequently residual perceptual abilities, which rely on delicate patterns of activity in the neurons, are often adversey affected. In this project, we seek to understand the functional neural circuits and their collaborative roles in processing sound in the early stages of the auditory pathway. We will also determine how these basic mechanisms are affected by hearing loss, and how hearing loss affects higher-order sensory processing in the brain. These experiments will ultimately generate insights for alternative stimulation strategies for the hard-of-hearing, and for cochlear implant users.
Funding type: research
Funder scheme: R01
Start date: 2000-09-01
End date: 2020-08-31
Investigator: PAUL B MANIS
Institution: UNIV OF NORTH CAROLINA CHAPEL HILL
Funded outputs count: 33
Funder award ID: R01DC004551
OpenAlex ID: G2182005359