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SPORE in Lymphoma

Description: OVERALL NARRATIVE Cellular immunotherapy has enormous potential to improve the therapy of lymphoma. The SPORE research plan outlined in this renewal application seeks to develop more effective cellular immunotherapies by increasing their antitumor activity against lymphomas in children and adults, reducing treatment-related complications, and simplying therapies to use banked allogeneic products that are immediately available. Results of these studies will lay the foundation for future comparative trials and licensing investigations.
Funding type: program
Funder scheme: P50
Start date: 2007-04-01
End date: 2027-08-31
Investigator: MALCOLM K. BRENNER
Institution: BAYLOR COLLEGE OF MEDICINE
Funded outputs count: 429
Funder award ID: P50CA126752
OpenAlex ID: G9000915301
2026 · David Steffin, Amy N. Courtney, et al. · New England Journal of Medicine
2026 · Rui Yang, Solomon K. Turunbedu, et al. · Journal of Human Immunity
2026 · Leonard Leong, Mansi Narula, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Gabriel A. Barragán Bravo, David A. de la Cerda, et al. · Molecular Therapy · 7
2026 · Benjamin L. Musher, Spyridoula Vasileiou, et al. · Nature Medicine · 11
2025 · Alan Hodges, Shu-Hsia Chen, et al. · Molecular Therapy Oncology
2025 · Roni Shouval, Christopher Strouse, et al. · Transplantation and Cellular Therapy · 31
2025 · Rayne H. Rouce, Bambi J. Grilley · Molecular Therapy · 23
2025 · Yomani D. Sarathkumara, Nathan W. Van Bibber, et al. · Blood Advances · 3
2025 · Srikanth Kodali, Caroline M. Sands, et al. · Nature reviews. Immunology · 12
2024 · Nader Kim El-Mallawany, Rayne H. Rouce · Hematology · 26
2024 · Daniel Goyco Vera, Hiral Waghela, et al. · Human Vaccines & Immunotherapeutics · 85
2024 · Rebecca A. Gardner, Claire White, et al. · Transplantation and Cellular Therapy · 12
2024 · David H. Quach, Haran R. Ganesh, et al. · Molecular Therapy Oncology · 12
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