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296840

Funded outputs count: 26
Funder award ID: 296840
OpenAlex ID: G1440975073
Functional polymorphisms in pigmentation-related genes MC1R and DCT display population-specific association with wet age-related macular degeneration
2026 · Mika Reinisalo, Seppo Helisalmi, et al. · Biochemistry and Biophysics Reports
Analysis of prognostic and predictive factors in neovascular age‐related macular degeneration Kuopio cohort
2024 · Hanna Heloterä, Leea Siintamo, et al. · Acta Ophthalmologica · 12
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PGC-1α Regulates the Interplay between Oxidative Stress, Senescence and Autophagy in the Aging Retina Important in Age-Related Macular Degeneration
2023 · Iswariyaraja Sridevi Gurubaran, Cezary Watala, et al. · Preprints.org · 1
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Oxidative Stress and Cellular Protein Accumulation Are Present in Keratoconus, Macular Corneal Dystrophy, and Fuchs Endothelial Corneal Dystrophy
2023 · Linda Vottonen, Ali Koskela, et al. · Journal of Clinical Medicine · 18
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Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients
2023 · Viivi Karema-Jokinen, Ali Koskela, et al. · Journal of Biological Chemistry · 21
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Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD)
2023 · Juha M. T. Hyttinen, Janusz Blasiak, et al. · International Journal of Molecular Sciences · 25
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A Linkage between Angiogenesis and Inflammation in Neovascular Age-Related Macular Degeneration
2022 · Hanna Heloterä, Kai Kaarniranta · Cells · 114
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Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells
2022 · Ali Koskela, Federico Manai, et al. · Antioxidants · 7
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Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions
2022 · Niina Bhattarai, Maria Hytti, et al. · Immunologic Research · 5
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Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study
2021 · Vanessa Derenji de Mello, Tuomas Selander, et al. · Nutrients · 13
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Epithelial–mesenchymal transition‐related serum markers ET‐1, IL‐8 and TGF‐β2 are elevated in a Finnish wet age‐related macular degeneration cohort
2021 · Mikko P. K. Liukkonen, Jussi J. Paterno, et al. · Acta Ophthalmologica · 19
Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α -/- Mouse Model Evoke Complement Component C5a Independent of C3
2021 · Iswariyaraja Sridevi Gurubaran, Hanna Heloterä, et al. · Biology · 12
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Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration
2021 · Maria Hytti, Eveliina Korhonen, et al. · International Journal of Molecular Sciences · 14
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TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells
2021 · Sofia Ranta-aho, Niina Piippo, et al. · International Journal of Molecular Sciences · 19
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Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
2021 · Janusz Blasiak, Ali Koskela, et al. · International Journal of Molecular Sciences · 24
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MicroRNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy
2021 · Juha M.T. Hyttinen, Janusz Blasiak, et al. · Ageing Research Reviews · 47
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[Retracted] Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice
2021 · Toni Tamminen, Ali Koskela, et al. · Oxidative Medicine and Cellular Longevity · 3
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Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
2020 · Kai Kaarniranta, Hannu Uusitalo, et al. · Progress in Retinal and Eye Research · 527
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Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model
2020 · Iswariyaraja Sridevi Gurubaran, Johanna Viiri, et al. · International Journal of Molecular Sciences · 50
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The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology
2019 · Juha M. T. Hyttinen, Ram Kannan, et al. · International Journal of Molecular Sciences · 72
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Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
2018 · Szabolcs Felszeghy, Johanna Viiri, et al. · Redox Biology · 155
Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage
2018 · Amna E. Abu Khamidakh, Alejandra Rodriguez-Martinez, et al. · BioMedical Engineering OnLine · 6
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Mechanistical retinal drug targets and challenges
2018 · Kai Kaarniranta, Heping Xu, et al. · Advanced Drug Delivery Reviews · 29
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Melatonin in Retinal Physiology and Pathology: The Case of Age‐Related Macular Degeneration
2016 · Janusz Blasiak, Russel J. Reiter, et al. · Oxidative Medicine and Cellular Longevity · 67
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