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R01-DK083491

Funded outputs count: 37
Funder award ID: R01-DK083491
OpenAlex ID: G1492615674
Nutrient-sensing mTORC1 and AMPK pathways in chronic kidney diseases
2022 · Christopher Huynh, Jaewhee Ryu, et al. · Nature Reviews Nephrology · 102
The molecular and metabolic program by which white adipocytes adapt to cool physiologic temperatures
2021 · Hiroyuki Mori, Colleen E. Dugan, et al. · PLoS Biology · 21
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Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
2020 · Yao Yao, Sungki Hong, et al. · Molecular Cell · 26
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AMPK directly activates mTORC2 to promote cell survival during acute energetic stress
2019 · Dubek Kazyken, Brian Magnuson, et al. · Science Signaling · 221
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR
2019 · Xiaoli Zhang, Wei Chen, et al. · PLoS Biology · 102
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mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism
2019 · Huibin Tang, Ken Inoki, et al. · Aging Cell · 193
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Loss of AMPKα2 Impairs Hedgehog-Driven Medulloblastoma Tumorigenesis
2018 · Honglai Zhang, Rork Kuick, et al. · International Journal of Molecular Sciences · 9
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Macropinocytosis, mTORC1 and cellular growth control
2017 · Sei Yoshida, Regina Pacitto, et al. · Cellular and Molecular Life Sciences · 113
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Microphthalmia-associated transcription factors activate mTORC1 through RagD GTPase gene expression
2017 · Edith Jones, Ken Inoki · Translational Cancer Research · 4
Lysosomal Regulation of mTORC1 by Amino Acids in Mammalian Cells
2017 · Yao Yao, Edith Jones, et al. · Biomolecules · 64
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Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress
2017 · Meiyan Jin, Gregory G. Fuller, et al. · Cell Reports · 208
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LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs
2017 · Sungki Hong, Mallory A Freeberg, et al. · eLife · 197
Aberrant mTORC1 activation kills tubular cells by inactivating miR148b-3p
2016 · Ken Inoki · Kidney International
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Evaluating the mTOR Pathway in Physiological and Pharmacological Settings
2016 · S. Hong, K. Inoki · Methods in enzymology on CD-ROM/Methods in enzymology · 8
mTOR: Pumping Nutrients into Tubules
2016 · Ken Inoki · Journal of the American Society of Nephrology
Role of Ragulator in the Regulation of Mechanistic Target of Rapamycin Signaling in Podocytes and Glomerular Function
2016 · Yao Yao, Junying Wang, et al. · Journal of the American Society of Nephrology · 21
The role of mechanistic target of rapamycin in maintenance of glomerular epithelial cells
2015 · Yao Yao, Ken Inoki · Current Opinion in Nephrology & Hypertension · 11
Growth factor signaling to mTORC1 by amino acid–laden macropinosomes
2015 · Sei Yoshida, Regina Pacitto, et al. · The Journal of Cell Biology · 104
GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury
2014 · Dae Won Park, Shaoning Jiang, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 84
Liver Clock Protein BMAL1 Promotes de Novo Lipogenesis through Insulin-mTORC2-AKT Signaling
2014 · Deqiang Zhang, Xin Tong, et al. · Journal of Biological Chemistry · 115
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Cross-talk between Sirtuin and Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in the Regulation of S6 Kinase 1 (S6K1) Phosphorylation
2014 · Sungki Hong, Bin Zhao, et al. · Journal of Biological Chemistry · 98
mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases
2014 · Huibin Tang, Ken Inoki, et al. · Science Signaling · 143
mTOR Signaling in Autophagy Regulation in the Kidney
2013 · Ken Inoki · Seminars in Nephrology · 69
Proximal Tubules Forget “Self-Eating” When They Meet Western Meals
2013 · Ken Inoki · Journal of the American Society of Nephrology
Inhibition of AMPK Catabolic Action by GSK3
2013 · Tsukasa Suzuki, Dave Bridges, et al. · Molecular Cell · 225
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