Award

PJT-479641

Funder: Canadian Institutes of Health Research

Funded outputs count: 8

Funder award ID: PJT-479641

OpenAlex ID: G1507464023

IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells

2026 · Roozbeh Akbari Motlagh, Nayara Rampazzo Morelli, et al. · Islets

Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort

2025 · Camille Préfontaine, Jasmine Pipella, et al. · Scientific Reports · 6

Secreted GDF15 maintains transcriptional responses during DNA damage-mediated senescence in human beta cells

2024 · Nayara Rampazzo Morelli, Camille Préfontaine, et al. · American Journal of Physiology-Endocrinology and Metabolism · 12

Exploring Transcriptional Regulation of Beta Cell SASP by Brd4-Associated Proteins and Cell Cycle Control Protein p21

2024 · Jasmine Manji, Jasmine Pipella, et al. · Epigenomes · 5

Protocol for quantifying SA-β-gal activity as a measure of senescence in islets of a mouse model of type 1 diabetes

2024 · Hugo Lee, Peter J. Thompson, et al. · STAR Protocols · 4

Establishing evidence for immune surveillance of β-cell senescence

2024 · Nayara Rampazzo Morelli, Jasmine Pipella, et al. · Trends in Endocrinology and Metabolism · 6

Stress-induced β cell early senescence confers protection against type 1 diabetes

2023 · Hugo Lee, Gulcan Semra Sahin, et al. · Cell Metabolism · 64

Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell

2023 · Peter J. Thompson, Jasmine Pipella, et al. · Diabetologia · 35