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GM 15431

Funded outputs count: 523
Funder award ID: GM 15431
OpenAlex ID: G1509819248
Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site
2019 · Shu Xu, Md. Jashim Uddin, et al. · Journal of Biological Chemistry · 25
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Oxidation of C18 Hydroxy‐Polyunsaturated Fatty Acids to Epoxide or Ketone by Catalase‐Related Hemoproteins Activated with Iodosylbenzene
2017 · Tarvi Teder, William E. Boeglin, et al. · Lipids · 7
Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
2016 · Olivier Boutaud, I. Romina Sosa, et al. · Cancer Prevention Research · 54
Cyclooxygenase-2 inhibition reduces stress-induced affective pathology
2016 · Joyonna Carrie Gamble-George, Rita Baldi, et al. · eLife · 55
Competition and allostery govern substrate selectivity of cyclooxygenase-2
2015 · Michelle M. Mitchener, Daniel J. Hermanson, et al. · Proceedings of the National Academy of Sciences · 32
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Robust inhibitory effects of conjugated linolenic acids on a cyclooxygenase-related linoleate 10S-dioxygenase: Comparison with COX-1 and COX-2
2015 · Zahra Mashhadi, William E. Boeglin, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 9
Action at a Distance
2015 · Anna L. Blobaum, Shu Xu, et al. · Journal of Biological Chemistry · 48
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13-Methylarachidonic Acid Is a Positive Allosteric Modulator of Endocannabinoid Oxygenation by Cyclooxygenase
2015 · Shalley N. Kudalkar, Spyros P. Nikas, et al. · Journal of Biological Chemistry · 30
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The structural basis for specificity in lipoxygenase catalysis
2014 · Marcia E. Newcomer, Alan R. Brash · Protein Science · 226
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Randomized, Placebo-Controlled Trial of Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis
2014 · David R. Janz, Julie A. Bastarache, et al. · Critical Care Medicine · 116
Oxicams, a class of nonsteroidal anti‐inflammatory drugs and beyond
2014 · Shu Xu, Carol A. Rouzer, et al. · IUBMB Life · 133
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Genetic Disruption of 2-Arachidonoylglycerol Synthesis Reveals a Key Role for Endocannabinoid Signaling in Anxiety Modulation
2014 · Brian C. Shonesy, Rebecca J. Bluett, et al. · Cell Reports · 155
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The isoprostanes—25 years later
2014 · Ginger L. Milne, Qi Dai, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 335
Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells
2014 · Joseph D. Manna, James A. Wepy, et al. · Journal of Biological Chemistry · 32
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Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction
2014 · Tarvi Teder, William E. Boeglin, et al. · Journal of Lipid Research · 15
Crystal Structure of a Lipoxygenase in Complex with Substrate
2014 · David B. Neau, Gunes Bender, et al. · Journal of Biological Chemistry · 78
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Protein Modification by Adenine Propenal
2014 · Sarah C. Shuck, Orrette R. Wauchope, et al. · Chemical Research in Toxicology · 8
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Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation
2014 · R J Bluett, J C Gamble-George, et al. · Translational Psychiatry · 157
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Levuglandin Forms Adducts with Histone H4 in a Cyclooxygenase-2-Dependent Manner, Altering Its Interaction with DNA
2014 · Erica J. Carrier, Irene Zagol-Ikapitte, et al. · Biochemistry · 33
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Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network
2014 · Shu Xu, Daniel J. Hermanson, et al. · Journal of Biological Chemistry · 125
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Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib
2013 · Matthew A. Windsor, Pieter L. Valk, et al. · Bioorganic & Medicinal Chemistry Letters · 22
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation
2013 · Daniel J Hermanson, Nolan D Hartley, et al. · Nature Neuroscience · 126
Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation
2013 · Maceler Aldrovandi, Victoria J. Hammond, et al. · Journal of Lipid Research · 52
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Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a)
2013 · Gregor Leibundgut, Corey Scipione, et al. · Journal of Lipid Research · 245
Epithelial-Specific Deletion of 11β-HSD2 Hinders Apcmin/+ Mouse Tumorigenesis
2013 · Li Jiang, Shilin Yang, et al. · Molecular Cancer Research · 11
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