Circulatory Rejuvenating Factors for the Brain
Description: PUBLIC HEALTH RELEVANCE: The proposed research will follow up on studies from our lab showing that blood from young mice can increase the generation of new neurons and improve cognition in old mice. We will test putative factors that can mimic this effect and carry out discovery projects to identify additional protein factors with regenerative and rejuvenating activity on the old brain. Halting or reversing brain aging by only a small fraction could have a significant impact not only on quality of life in older persons but possibly delay neurodegenerative processes and dementia.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2013-06-01
End date: 2018-05-31
Investigator: TONY WYSS-CORAY
Institution: PALO ALTO VETERANS INSTIT FOR RESEARCH
Funded outputs count: 34
Funder award ID: R01AG045034
OpenAlex ID: G6531741886