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Multicomponent intervention to improve delirium and sleep-wake rhythms in older ICU patients

Description: Page 1 of 12 (remove for final draft) PROJECT NARRATIVE Older adults (≥65 years old) now comprise the majority of patients in intensive care units (ICUs). In the ICU setting, these older patients frequently experience delirium and misaligned sleep-wake rhythms, placing them at high risk of poor outcomes after ICU discharge. In this proposed study, we will enroll an interdisciplinary team to implement a multicomponent nighttime and daytime intervention in two academic ICUs, with the goal of improving delirium and sleep-wake rhythms (as measured using wrist actigraphy) in vulnerable older ICU patients.
Funding type: career_development
Funder scheme: K76
Start date: 2018-09-01
End date: 2024-05-31
Investigator: BIREN BHARAT KAMDAR
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Field: Medicine
Funded outputs count: 43
Funder award ID: K76AG059936
OpenAlex ID: G3003681093
2025 · Biren B. Kamdar · New England Journal of Medicine
2025 · Liz Timple, Sanil Gandhi, et al. · Sleep Medicine Clinics
2025 · Ana Lucia Fuentes, Charlotte C. Ellberg, et al. · CHEST Critical Care · 2
2025 · Biren B. Kamdar · American Journal of Hospice and Palliative Medicine®
2025 · Biren B. Kamdar · Journal of the American Geriatrics Society
2025 · Onyekachi S. Ezeokeke, Janelle M. Fine, et al. · Journal of Clinical Sleep Medicine
2025 · Nikhil Chilakapati, Liz Timple, et al. · Chronobiology International · 12
2024 · Han Su, Ana Lucia Fuentes, et al. · Critical Care Clinics · 24
2024 · Jamie Nicole LaBuzetta, Dale N. Bongbong, et al. · Neurocritical Care · 4
2024 · Ana Lucia Fuentes, Hirsh Makhija, et al. · ATS Scholar · 1
2023 · Michael E. Reznik, Noa Mintz, et al. · Journal of the Neurological Sciences · 1
2023 · Hirsh Makhija, Janelle M. Fine, et al. · Critical Care Explorations · 7
2023 · Biren B Kamdar, Janelle M Fine, et al. · Journal of the Intensive Care Society · 4
2023 · Melissa P. Knauert, Najib T. Ayas, et al. · American Journal of Respiratory and Critical Care Medicine · 107
2023 · Jamie Nicole LaBuzetta, Biren B. Kamdar, et al. · Journal of Clinical Neuroscience · 13
2022 · Jamie Nicole LaBuzetta, Max R. Kazer, et al. · The Neurologist · 4
2022 · Jiha Lee, Biren B. Kamdar, et al. · Journal of the American Geriatrics Society · 4
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